Contains the active ingredients Lamivudine, Nevirapine, and Zidovudine.
A combination of three antiretroviral medicines.
Used to treat HIV-1 infection.
Important Information:
Not advised for patients with anemia (low red blood cells) or neutropenia (low white blood cells).
Inform your doctor if you have liver disease, including hepatitis B or C, kidney disease, or are overweight.
The medication is not recommended for children less than 35 kg.
May cause decreased fertility in females.
Not recommended if you are allergic to this drug or any other active substance, or if you are pregnant or breastfeeding.
Therapeutic Effects:
Lamivudine and Zidovudine inhibit the reverse transcriptase enzyme of HIV, restricting viral genome replication and reducing the production of new infectious viral particles.
Nevirapine directly binds to reverse transcriptase (RT) and blocks RNA-dependent and DNA-dependent polymerase activities by disrupting the enzyme.
Interaction with Other Drugs:
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional supplements, and herbal products.
Certain medications may exacerbate the toxicity of Zidovudine or reduce the effectiveness of Zidolam N.
Storage:
Store Zidolam N below 30°C.
Keep the medicine out of reach of children and pets.
How to Consume:
Take as advised by your physician.
Swallow the tablets whole and intact.
Take with food.
Do not crush, chew, or open the medicine.
Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Safety Advices:
Pregnancy: Do not take if you are in your first trimester. Consult your physician if you are pregnant, suspecting, or planning to get pregnant during treatment.
Breastfeeding: Breastfeeding is not recommended during treatment.
Lungs: It is unknown whether Zidolam N is safe for patients with lung diseases. Consult your physician if you have any lung diseases.
Liver: Use cautiously in patients with liver diseases. Dose adjustments are necessary.
Alcohol: It is unknown whether consuming alcohol while taking Zidolam N is safe. Consult your physician.
Driving: It is unknown whether Zidolam N alters the ability to drive or operate heavy machinery. If you feel sleepy or dizzy, avoid driving and consult your doctor.
Side Effects:
Serious: Lactic acidosis, severe skin reactions, liver problems, osteonecrosis, symptoms of muscle weakness or infection, loss of fat from legs, face, and arms.
Q1: Can I stop taking Zidolam N once I feel better?
A: No, continuing as prescribed is important, even if you feel better. Stopping or interrupting treatment can lead to viral rebound and the development of drug resistance.
Q2: Can Zidolam N cure HIV?
A: No, Zidolam N cannot cure HIV. They are used as part of combination antiretroviral therapy (ART) to suppress the virus, improve the immune system, and prevent the progression of HIV infection. ART is a lifelong treatment for HIV.
Q3: Can Zidolam N prevent HIV transmission during unprotected sex?
A: While Zidolam N is effective in managing HIV infection, they are not intended to prevent HIV transmission. It is necessary to use preventive measures like condoms to reduce the chance of acquiring HIV.
Q4: Does Zidolam N cause bone marrow suppression?
A: Yes, Zidolam N may cause bone marrow suppression. Inform your physician if you experience any changes in your blood reports, such as increased or decreased RBC and WBC.
Q5: Can Zidolam N be given to kidney failure patients?
A: Zidolam N should be used with caution in patients with kidney diseases. Inform your physician if you have any kidney diseases before initiating treatment.