Xgeva 120mg Injection
Active ingredient: Denosumab
Uses:
- Osteoporosis
- Bone loss due to hormonal therapy in breast or prostate cancer
- Multiple myeloma (cancer affecting plasma cells in the bone marrow)
- Bone metastases (cancer that spreads to bone)
Therapeutic effects:
- Reducing fracture risk
- Increasing bone mineral density
- Improving overall bone health
Administration:
- Given as an injection by healthcare professionals
- Dosage and duration determined by a healthcare provider
Storage:
- Store in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F)
- Do not freeze
- Keep in the original package
- Keep away from light, moisture, and heat
- Keep away from children and pets
Safety advice:
- Pregnancy: the safety of using Xgeva 120mg Injection during pregnancy has not been established. Consult a doctor before use.
- Breastfeeding: consult a healthcare provider before taking this medication.
- Lungs: consult your healthcare provider if you have a lung or respiratory disorder history.
- Liver: Xgeva 120mg Injection is primarily metabolized in the liver, and its safety has not been extensively studied in individuals with severe liver impairment.
- Alcohol: avoid or limit alcohol consumption while taking Xgeva 120mg Injection.
- Driving: avoid driving or operating machinery if you experience side effects such as fatigue, dizziness, or blurred vision.
Side effects:
- Serious: osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia
- Common: injection site reactions, back pain, musculoskeletal pain, infections, abdominal pain, headache, hypophosphatemia
FAQs:
Can Xgeva 120mg Injection be used in patients with a history of cancer? Xgeva 120mg Injection is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. Discuss your medical history with your healthcare provider.
Can Xgeva 120mg Injection be used in patients with kidney problems? Caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits.
Can Xgeva 120mg Injection be used as a treatment for osteoporosis in men? Yes, Xgeva 120mg Injection is approved for the treatment of osteoporosis in men at increased risk of fractures.
Can Xgeva 120mg Injection be used in children and adolescents with osteoporosis? Xgeva 120mg Injection is not approved for use in children and adolescents with osteoporosis.
Can Xgeva 120mg Injection be used in individuals with dental implants? Xgeva 120mg Injection use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Discuss this with your dentist and healthcare provider.
What are the side effects of Xgeva 120mg Injection? Xgeva 120mg Injection can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.
Fact box:
- Molecule name: Denosumab
- Therapeutic class: Anti-resorptive agent
- Pharmacological class: Monoclonal Antibodies
- Indications: Osteoporosis, bone loss due to hormonal therapy in breast or prostate cancer, multiple myeloma, bone metastases