Versavo 400mg Injection is an anticancer medicine consisting of the active ingredient Bevacizumab.
It is developed to prevent the growth of tumors and is indicated along with other chemotherapy drugs to treat various types of cancer.
Uses:
Metastatic breast cancer
Brain cancer (glioblastoma multiforme)
Cervical cancer
Kidney cancer
Lung cancer
Colorectal cancer
Ovarian cancer
Fallopian tube cancer
Primary peritoneal cancer
Therapeutic Effects:
Versavo 400mg Injection works as a targeted therapy by selectively binding to the protein called vascular endothelial growth factor A (VEGF-A).
It inhibits the formation of blood vessels that supply oxygen and nutrients to the tumor, slowing down the rate of progression of cancer.
Administration:
Administered intravenously by a physician or nurse.
The infusion should be given immediately after the dilution.
Safety Advice:
Not recommended for adolescents and children under the age of 18.
Use effective birth control during treatment and for at least six months after the last dose.
Discuss with your doctor about the preservation of ovaries if you are planning for pregnancy in the near future.
Avoid breastfeeding for a minimum of 6 months after treatment.
Inform your doctor if you have any lung or liver conditions.
Consult your doctor to know if it is safe to consume alcohol while on treatment.
Avoid driving or using machinery due to potential dizziness or sleepiness.
Interaction with other drugs:
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment.
Storage:
Store Versavo 400mg Injection at 2˚C to 8˚C.
Do not freeze or shake.
Protect from light.
Keep out of reach of children.
Side Effects:
Serious: headache, vision changes, confusion, severe allergic reactions, high blood pressure, delayed wound healing following surgery, protein in urine, severe infections, blood clots in arteries and blood vessels of lungs, gut perforation, nosebleeds and bleeding risk, heart problems with an increase in heart rate, mouth sores, dryness, shortness of breath.
Common: numbness in hands or feet, weakness and lack of energy, diarrhea, nausea, vomiting, abdominal pain, constipation, loss of appetite, weight loss, changes in taste and speech, decrease in counts of white blood cells, fever, dry skin, back pain.
FAQs:
Is Versavo 400mg Injection used as standalone treatment in cancers?
Versavo 400mg Injection can be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.
Is it safe for women to use Versavo 400mg Injection?
Women with reproductive potential should discuss with their doctor regarding effective birth control methods during treatment and for at least 6 months after completion.
Is it safe to undergo surgery during the treatment with Versavo 400mg Injection?
Versavo 400mg Injection is associated with increased risk of bleeding complications and poor wound healing. Avoid surgery and maintain an interval of 28 days before or after surgery.
Do the side effects of Versavo 400mg Injection last for a chronic period?
Side effects occur until the drug concentration stays in the body. The medicine will be contained in the body for about 4 months after the final dose.
How is Versavo 400mg Injection administered?
Versavo 400mg Injection is given intravenously through infusion. The amount of drug will be measured based on the patient’s body weight, height, and age. The first dose will be administered for 90 minutes, and if well tolerated, the infusion time can be reduced to 30 minutes.
Can I take Versavo 400mg Injection if I am pregnant?
Inform your physician before starting treatment with Versavo 400mg Injection if you are pregnant or planning for pregnancy, as this medicine may cause harm to the unborn baby.
Fact Box:
Molecule name: Bevacizumab
Therapeutic class: Anticancer
Pharmacological class: VEGF Inhibitor
Indications:
Glioblastoma multiforme (brain cancer)
Persistent, recurrent, or metastatic breast cancer
Metastatic cervical cancer
Advanced kidney cancer
Metastatic colorectal cancer
Advanced non-small-cell lung cancer
Liver Cancer- Hepatocellular carcinoma
Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer
