Uses of Trumab 440mg Injection
- Advanced and metastatic breast cancer.
- Metastatic gastric cancer with increased levels of HER2 proteins.
Therapeutic Effects
- Trumab 440mg Injection binds to HER2 proteins, which are overexpressed in certain breast cancer cells, and inhibits their growth.
Important Information
- Age Restrictions: Not recommended for patients under 18 years of age.
- Contraindications: Not suitable for patients with severe breathing problems or those requiring oxygen treatment.
- Medical History: Inform your physician about any heart problems, breathlessness, or previous cancer treatments.
- Medication Interactions: Inform your doctor about all medications, including supplements and herbal medicines, you are taking.
- Storage: Store between 2˚C and 8˚C, out of sight and reach of children.
Administration
- Administered intravenously, either before or after surgery.
- Initial infusion time is 90 minutes; if well tolerated, subsequent doses can be given within 30 minutes.
Safety Advice
- Pregnancy: Discuss with your physician before taking this medication if you are pregnant or might be pregnant.
- Breastfeeding: Avoid breastfeeding while on treatment and for at least seven months after the final dose.
- Lungs: Consult your doctor if you have any lung conditions before starting treatment.
- Liver: Inform your physician of any liver disorders; dosage adjustment may be required for severe liver impairment.
- Alcohol: Consult your doctor to know if it is safe to consume alcohol while on treatment.
- Driving: Avoid driving or handling machinery during treatment due to potential side effects like dizziness and fatigue.
Side Effects
- Serious: Heart problems, allergic reactions, kidney problems, breathing difficulties.
- Common: Fever, visual disturbances, nose bleeds or runny nose, hair loss, dizziness, nail disorders, weight loss, loss of appetite, bruising, dry mouth, liver inflammation, muscle pain, asthma/lung disorders.
Word of Advice
- Inform your doctor if you have a history of allergic reactions to Trumab 440mg Injection.
- If you have a history of lung disorder or breathing problems, inform your doctor before treatment commencement.
- Avoid pregnancy and breastfeeding for a minimum of 7 months after the last dose.
- Monitor heart parameters regularly during treatment.
FAQs
Q 1. Is Trumab 440mg Injection used as a monotherapy in treating breast cancer? Trumab 440mg Injection is generally given along with chemotherapy medications such as paclitaxel or docetaxel or platinum compounds. Sometimes, it is also given with hormonal agents for those patients with elevated hormonal status.
Q 2. Does Trumab 440mg Injection cause heart problems? Yes, Trumab 440mg Injection can damage the heart muscles. Hence, it is advised to do a heart check-up every 3 months and continue till 2-5 years after the treatment completion.
Q 3. Can I breastfeed while on treatment with Trumab 440mg Injection? No, since the medication tends to pass into breast milk, it is unsafe to breastfeed. Hence, it is advised not to breastfeed for a minimum of 7 months after the treatment with Trumab 440mg Injection.
Q 4. Can Trumab 440mg Injection be consumed during pregnancy? No, it is unsafe to consume Trumab 440mg Injection while you are pregnant as it can cause harm to the baby. If you are planning for pregnancy, it is advised to discuss birth control methods with your doctor.
Fact Box
- Molecule name: Trastuzumab.
- Therapeutic class: Anti-cancer.
- Pharmacological class: HER2 inhibitor.
- Indications:
- Advanced and metastatic breast cancer.
- Metastatic gastric cancer.