Rheumatoid arthritis (a condition in which the body attacks its joints, causing pain, swelling, and loss of function).
Psoriatic arthritis (a condition that causes joint pain and swelling, and scales on the skin).
Ankylosing spondylitis (inflammatory disease of the spine).
Ulcerative colitis (treatment of adult patients with moderately to severely active ulcerative colitis).
Polyarticular juvenile idiopathic arthritis (a long-term disease mainly causing pain and swelling of your joints in patients 2 years of age and older).
Juvenile psoriatic arthritis.
How it works:
Tofashine XR 11mg Tablet is a disease-modifying anti-rheumatic drug (DMARD) in the category of Janus Kinase Inhibitors.
It works by inhibiting Janus kinases and interferes with the transcription of genes involved in cell growth and differentiation.
Important information:
Do not take Tofashine XR 11mg Tablet if you are allergic to tofacitinib or any other ingredients of this medicine.
Inform your healthcare professional if you have any symptoms of an infection, such as fever, sweating, chills, muscle aches, cough, shortness of breath, weight loss, skin sores, difficulty or pain when swallowing, diarrhea, or stomach pain.
Before initiating the treatment, inform your physician if you have kidney, heart, lung, or liver problems, a history of tuberculosis, high blood pressure, or high cholesterol, and also if you are a current or past smoker.
Interaction with other drugs:
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, vaccinations, nutritional and vitamin supplements, and herbal products.
Storage:
Store tofacitinib at room temperature (20°C to 25°C).
Keep the tablet away from the reach of children and pets.
Dosage and administration:
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors.
Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water.
Take the tablet with or without food.
Safety advice:
Pregnancy: Tofashine XR 11mg Tablet is unsafe to administer in pregnant women because it may affect the fetus.
Breastfeeding: Breastfeeding is not recommended in patients taking Tofashine XR 11mg Tablet because the medicine passes into the breast milk in small amounts and may harm your baby.
Lungs: It is unknown whether Tofashine XR 11mg Tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver: Tofashine XR 11mg Tablet is unsafe when administered in patients with severe liver diseases. Dose adjustments are necessary in severe liver failure.
Alcohol: It is unknown whether it is safe to consume alcohol when taking Tofashine XR 11mg Tablet. Consult your doctor for more advice.
Driving: The drug has no or limited effect on your ability to drive or operate heavy machines. If you face any difficulties, consult your doctor for more advice.
Side effects:
Common: increased cholesterol levels, headache, painful urination, inflammation of the nose, cough, shortness of breath, diarrhea, skin rashes.
Serious: lung cancer, white blood cell cancer, heart attack, fever and chills, blood in the stool, stomach pain or abdominal pain, skin blisters.
FAQ:
Q1. What are the cautions of Tofashine XR 11mg tablet?
Tell your doctor immediately if you start to have swelling of your face, lips, tongue, throat, arms, or legs or if you are having trouble swallowing or breathing. Tofashine XR 11mg tablet can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection.
Q2. Does Tofashine XR 11mg tablet cause high cholesterol?
Increased cholesterol levels are one of the side effects of Tofashine XR 11mg tablet, your doctor may take regular blood tests to check for serious side effects.
Q3. Can Tofashine XR 11mg tablet cause depression?
No, Tofashine XR 11mg tablet does not cause depression. However, many people who have autoimmune conditions also have symptoms of depression. If you're having symptoms of depression, see your doctor right away.
Q4. Does Tofashine XR 11mg tablet cause blood clots?
Yes, blood clots are reported in patients using Tofashine XR 11mg tablet for a longer period. Inform your physician if you face any symptoms of a blood clot.
Q5. How long does it take Tofashine XR 11mg tablet to work?
Tofashine XR 11mg tablet is a long-term treatment. Most people who benefit from this treatment will notice an improvement in the first 12 weeks of starting treatment.
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