Rheumatoid arthritis (a condition in which the body attacks its joints, causing pain, swelling, and loss of function).
Psoriatic arthritis (a condition that causes joint pain and swelling, and scales on the skin).
Ankylosing spondylitis (inflammatory disease of the spine).
Ulcerative colitis (a condition affecting the colon and rectum).
Polyarticular juvenile idiopathic arthritis (a long-term disease mainly causing pain and swelling of joints in patients 2 years of age and older).
Juvenile psoriatic arthritis.
Therapeutic Effects:
TFCT NIB OD tablet is a disease-modifying anti-rheumatic drug (DMARD) in the category of Janus Kinase Inhibitors.
It works by inhibiting Janus kinases and interferes with the transcription of genes involved in cell growth and differentiation.
Interaction with other drugs:
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, vaccinations, nutritional and vitamin supplements, and herbal products.
Certain medications may interact with the effects of TFCT NIB OD tablet and reduce its effectiveness by causing undesirable side effects.
Storage:
Store tofacitinib at room temperature (20°C to 25°C).
Keep the tablet away from the reach of children and pets.
Dosage and Administration:
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors.
Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water.
Take the tablet with or without food.
If you forgot to take a dose, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up a forgotten dose.
Safety Advices:
Pregnancy: TFCT NIB OD tablet is unsafe to administer in pregnant women because it may affect the fetus.
Breastfeeding: Breastfeeding is not recommended in patients taking TFCT NIB OD tablet.
Lungs: It is unknown whether TFCT NIB OD tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver: TFCT NIB OD tablet is unsafe when administered in patients with severe liver diseases. Dose adjustments are necessary in severe liver failure.
Alcohol: It is unknown whether it is safe to consume alcohol when taking TFCT NIB OD tablet. Consult your doctor for more advice.
Driving: The drug has no or limited effect on your ability to drive or operate heavy machines. If you face any difficulties, consult your doctor for more advice.
Side Effects:
Common: increased cholesterol levels, headache, painful urination, inflammation of the nose, cough, shortness of breath, diarrhea, skin rashes.
Serious: lung cancer, white blood cell cancer, heart attack, fever and chills, blood in the stool, stomach pain or abdominal pain, skin blisters.
Word of Advice:
This medicine may interfere with vaccines, inform your physician about your vaccination history.
This medicine may impair fertility; talk to your doctor before taking this medicine.
Your doctor will regularly do lab tests to check whether the medicine is working.
Do not breastfeed during the treatment with this medicine and for at least 36 hours after your last dose.
This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.
FAQs:
What are the cautions of TFCT NIB OD tablet?
Tell your doctor immediately if you start to have swelling of your face, lips, tongue, throat, arms, or legs or if you are having trouble swallowing or breathing.
TFCT NIB OD tablet can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection.
Does TFCT NIB OD tablet cause high cholesterol?
Increased cholesterol levels are one of the side effects of TFCT NIB OD tablet, your doctor may take regular blood tests to check for serious side effects.
Can TFCT NIB OD tablet cause depression?
No, TFCT NIB OD tablet does not cause depression. However, many people who have autoimmune conditions also have symptoms of depression. If you're having symptoms of depression, see your doctor right away.
Does TFCT NIB OD tablet cause blood clots?
TFCT NIB OD tablet is a long-term treatment. Most people who benefit from this treatment will notice an improvement in the first 12 weeks of starting treatment.