Belongs to the class of immunosuppressants called calcineurin inhibitors.
Used along with other medications to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants.
Also indicated to control the body’s immune response, enabling it to accept the transplanted organ.
Usage:
Do not take if allergic to Tacrolimus or any other ingredients.
Inform your doctor if you have liver or heart disease before starting treatment.
Notify your physician immediately if you develop fever, bruising under the skin, unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine.
Therapeutic Effects:
Provides immunosuppression by inhibiting T-lymphocyte activation and proliferation and T-helper-cell-dependent B-cell response.
Works by attaching to a protein called FKBP-12 and forms a complex called tacrolimus-FKBP, which inhibits the action of calcineurin phosphatase.
Inhibits the formation of T cells and suppresses the immune response.
Interaction with Other Drugs:
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, vaccinations, nutritional and vitamin supplements, and herbal products.
Avoid grapefruit or grapefruit juice while taking this medicine.
Safety Advice:
Pregnancy: based on animal studies, Tacromus 2mg Capsule can cause harmful effects on the baby.
Breastfeeding: do not consume Tacromus 2mg Capsule if you are breastfeeding.
Lungs: it is unknown whether Tacromus 2mg Capsule can be used in patients with lung disorders.
Liver: Tacromus 2mg Capsule should be cautiously administered in patients with severe liver diseases.
Alcohol: it is unsafe to consume alcohol when taking Tacromus 2mg Capsule.
Driving: driving vehicles or operating machinery while taking Tacromus 2mg Capsule is unsafe.
Storage:
Store Tacromus 2mg Capsule at 25°C.
Keep the capsule away from the reach of children and pets.
If you miss a dosage, take it as soon as you remember. If it is almost time for the next dose, skip the missing dose. Do not take a double dose to compensate for a missed dose.
How to Consume:
Always take Tacromus 2mg Capsule as prescribed by your doctor.
Do not open, break, crush, or chew the capsules.
Swallow the capsule whole with a glass of water.
Take these capsules on an empty stomach or at least 1 hour before or 2 to 3 hours after the meal.
Side Effects:
Common: swelling in the arm or leg, hair loss, itchy skin, constipation, diarrhea, nausea, vomiting, anemia, headache, cough.
Serious: increased or decreased heartbeats, GI bleeding, liver injury, seizure, acute kidney failure, lung infection or respiratory problems.
Word of Advice:
Do not eat grapefruit or drink grapefruit juice while you are using Tacromus 2mg Capsule.
Do not drink alcohol while you are using this medicine.
This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines.
You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor.
FAQs:
What if I missed a dose of Tacromus 2mg Capsule?
Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.
What should you not use with Tacromus 2mg Capsule?
Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.
How long do I need to take Tacromus 2mg Capsule after a transplant?
The duration of Tacromus 2mg Capsule treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual’s response to the medication. In most cases, Tacromus 2mg Capsule is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.
Can Tacromus 2mg Capsule increase the risk of infections?
Yes, Tacromus 2mg Capsule can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.
Can Tacromus 2mg Capsule affect kidney function?
Tacromus 2mg Capsule must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.
Should I follow any dietary restrictions while taking Tacromus 2mg Capsule?
Tacromus 2mg Capsule can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.