Syndyma 100mg Injection
Uses:
- Glioblastoma multiforme (brain cancer);
- Persistent, recurrent, or metastatic breast cancer;
- Metastatic cervical cancer;
- Advanced kidney cancer;
- Metastatic colorectal cancer;
- Advanced non-small-cell lung cancer;
- Liver cancer — hepatocellular carcinoma;
- Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer.
Therapeutic Effects:
Syndyma 100mg Injection is a recombinant humanized monoclonal antibody that works as a targeted therapy in the treatment of various advanced cancers. It selectively binds to the protein called vascular endothelial growth factor A (VEGF-A), interrupting its interaction with receptors and inhibiting the formation of blood vessels that supply oxygen and nutrients to the tumor. This slows down the rate of progression of cancer.
Interaction with Other Drugs:
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Syndyma 100mg Injection and cause undesirable side effects.
Safety Advice:
- Pregnancy: Inform your physician before starting treatment with Syndyma 100mg Injection if you are pregnant or planning for pregnancy.
- Breastfeeding: It is recommended to avoid breastfeeding for a minimum of 6 months after treatment with Syndyma 100mg Injection.
- Lungs: Inform your doctor if you have any lung conditions before starting treatment.
- Liver: Inform your physician before starting Syndyma 100mg Injection if you have liver diseases.
- Alcohol: Consult your doctor to know if it is safe to consume alcohol while you are on treatment with Syndyma 100mg Injection.
- Driving: Avoid driving or using machinery while you are on treatment with Syndyma 100mg Injection, as it may cause dizziness or sleepiness.
Side Effects:
- Serious: headache, vision changes, confusion, severe allergic reactions, high blood pressure, delayed wound healing following surgery, protein in urine, severe infections, blood clots in arteries and blood vessels of lungs, gut perforation, nosebleeds and bleeding risk, heart problems with an increase in heart rate, mouth sores, dryness, shortness of breath.
- Common: numbness in hands or feet, weakness and lack of energy, diarrhoea, nausea, vomiting, abdominal pain, constipation, loss of appetite, weight loss, changes in taste and speech, decrease in counts of white blood cells, fever, dry skin, back pain.
Administration:
Syndyma 100mg Injection is given intravenously through infusion. The amount of drug will be measured based on the patient’s body weight, height, and age. The first dose will be administered for 90 minutes, and if well tolerated, the infusion time can be reduced to 30 minutes.
FAQ:
Is Syndyma 100mg Injection used as a standalone treatment in cancers? Syndyma 100mg Injection can be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.
Is it safe for women to use Syndyma 100mg Injection? While for women with reproductive potential, it is advised to discuss with your doctor regarding effective birth control methods during the treatment. Also, to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.
Is it safe to undergo surgery during the treatment with Syndyma 100mg Injection? Syndyma 100mg Injection is associated with an increased risk of bleeding complications and poor wound healing. Hence, it is suggested to avoid planning for surgery and maintain an interval of 28 days before or after surgery.
Do the side effects of Syndyma 100mg Injection last for a chronic period? All the side effects relatively caused by Syndyma 100mg Injection occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.
How is Syndyma 100mg Injection administered? Syndyma 100mg Injection is given intravenously through infusion, and the amount of drug will be measured based on the patient’s body weight, height, and age. The first dose will be administered for 90 minutes, and if well tolerated, the infusion time can be reduced to 30 minutes.
Can I take Syndyma 100mg Injection if I am pregnant? Inform your physician before starting your treatment with Syndyma 100mg Injection in case you are pregnant or planning for pregnancy, as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.
Fact Box:
- Molecule name: Bevacizumab.
- Therapeutic class: Anticancer.
- Pharmacological class: VEGF Inhibitor.