Sutent 12.5mg Capsule
Active ingredient: Sunitinib
Classification: Tyrosine kinase inhibitor
Mechanism of action: Blocks certain enzymes called tyrosine kinases that are involved in the growth and spread of cancer cells.
Uses:
- Renal cell carcinoma (RCC)
- Gastrointestinal stromal tumors (GIST)
- Pancreatic neuroendocrine tumors (PNET)
- Medullary thyroid cancer
- Certain kidney cancer
Therapeutic effects:
- Slowing down or stopping the growth and spread of cancer cells in the body
- Reducing the size and number of tumors
Interaction with other drugs:
- Consult with a physician about any existing medical conditions and current medications
- Avoid taking grapefruit or grapefruit juice during treatment
Storage:
- Store at room temperature, between 68°F and 77°F (20°C and 25°C)
- Keep in the original package
- Protect from moisture, light, and heat
- Keep out of reach from children and pets
How to consume:
- Taken orally, in the form of capsules, with a glass of water
- Swallow whole, do not crush, chew, or open
- Usually taken once a day, with or without food, at around the same time each day
- If you miss a dose, do not double the dose to compensate
Safety advices:
- Pregnancy: not recommended during pregnancy as it can cause harm to the developing fetus
- Breastfeeding: discuss the potential risks and benefits with a healthcare provider
- Lungs: can cause interstitial lung disease (ILD), a serious and potentially fatal condition that causes scarring of the lungs
- Liver: can cause liver toxicity, which can be severe or fatal in some cases
- Alcohol: avoid consuming alcohol during treatment
- Driving: avoid driving or operating machinery if experiencing side effects such as fatigue, dizziness, or blurred vision
Side effects:
- Serious: heart failure or heart attack, elevated liver function tests, liver failure, proteinuria, acute kidney injury, interstitial lung disease, pulmonary arterial hypertension, gastrointestinal perforation or fistula, haemorrhage (bleeding), hypothyroidism (low thyroid function), hypoglycemia (low blood sugar)
- Common: fatigue, nausea and vomiting, diarrhoea, loss of appetite, hand-foot syndrome, skin discoloration or rash, high blood pressure, headache, hair loss, changes in taste, dry skin or itching, nosebleeds
Word of advice:
- Follow your healthcare provider's instructions
- Avoid taking grapefruit or grapefruit juice
- Use a reliable method of birth control while taking the medication and for at least four weeks after the last dose
FAQs:
Can Sutent 12.5mg Capsule cause changes in skin color? Yes, Sutent 12.5mg Capsule can cause changes in skin color. One common side effect is called "hand-foot syndrome," which can cause redness, swelling, and pain in the palms of the hands and soles of the feet. In some cases, this syndrome can also cause the skin to darken or become thickened in these areas. Additionally, this medication can cause other skin changes, such as rashes and discoloration.
Can Sutent 12.5mg Capsule cause heart problems? Yes, Sutent 12.5mg Capsule can cause heart problems such as high blood pressure, heart failure, and heart attack. Patients taking this medication should be closely monitored by their healthcare provider for any signs of heart problems and may need to undergo regular heart function tests.
Can Sutent 12.5mg Capsule cause kidney problems? Yes, Sutent 12.5mg Capsule can cause kidney problems such as proteinuria (excess protein in the urine) and renal impairment. Patients taking this medication require regular monitoring of kidney function and need to adjust the dosage or switch to a different medication if these side effects occur or persist.
Can I take Sutent 12.5mg Capsule if I have a thyroid problem? Yes, but your healthcare provider will monitor your thyroid function regularly. Sutent 12.5mg Capsules can affect the thyroid gland, causing hypothyroidism (an underactive thyroid gland) or hyperthyroidism (an overactive thyroid gland). Therefore, your healthcare provider will check thyroid hormone levels in your blood before starting treatment, and periodically during treatment.
Can Sutent 12.5mg Capsule affect fertility? Yes, Sutent 12.5mg Capsules can affect fertility in both men and women. Patients taking this medication should discuss the potential risks and options for preserving fertility with their healthcare provider before starting treatment.
How can Sutent 12.5mg Capsule affect my blood? Sutent 12.5mg Capsules can cause hematologic toxicity, which may include neutropenia (low white blood cell count), thrombocytopenia (low platelet count), and anemia (low red blood cell count). These changes can increase the risk of infection, bleeding, and fatigue, respectively.
Fact box:
- Molecule name: Sunitinib
- Therapeutic class: Anticancer
- Pharmacological class: Tyrosine kinase inhibitor