Sunixar 12.5mg Capsule
Active ingredient: Sunitinib
Classification: Tyrosine kinase inhibitor
Mechanism of action: Blocks certain enzymes called tyrosine kinases that are involved in the growth and spread of cancer cells.
Uses:
- Renal cell carcinoma (RCC)
- Gastrointestinal stromal tumors (GIST)
- Pancreatic neuroendocrine tumors (PNET)
- Medullary thyroid cancer
- Certain kidney cancer
Important information:
- Not recommended for people under 18.
- Discuss with physician if you have blood conditions, heart problems, liver disorders, kidney problems, skin disorders, diabetes, seizures, or thyroid disorders.
- Inform if you have recently had surgery or are about to have surgery.
- Avoid taking grapefruit in any form during treatment.
- Check with dentist if you have any problems in the mouth before starting treatment.
Storage:
- Store at room temperature, between 68°F and 77°F (20°C and 25°C).
- Keep in the original package.
- Protect from moisture, light, and heat.
- Keep out of reach from children and pets.
How to consume:
- Taken orally, in the form of capsules, with a glass of water.
- Swallow whole, do not crush, chew, or open.
- Recommended dose may vary depending on the type of cancer being treated, the patient's age and weight, and other factors.
- Usually taken once a day, with or without food, at around the same time each day.
- If you miss a dose, do not double the dose to compensate.
Safety advices:
- Pregnancy: unsafe for a developing fetus.
- Breast feeding: discuss the potential risks and benefits with healthcare provider.
- Lungs: can cause interstitial lung disease (ILD).
- Liver: can cause liver toxicity.
- Alcohol: avoid consuming alcohol during treatment.
- Driving: avoid driving or operating machinery if experiencing side effects such as fatigue, dizziness, or blurred vision.
Side effects:
- Serious: heart failure or heart attack, elevated liver function tests, liver failure, proteinuria, acute kidney injury, interstitial lung disease, pulmonary arterial hypertension, gastrointestinal perforation or fistula, haemorrhage, hypothyroidism, hypoglycemia.
- Common: fatigue, nausea and vomiting, diarrhoea, loss of appetite, hand-foot syndrome, skin discoloration or rash, high blood pressure, headache, hair loss, changes in taste, dry skin or itching, nosebleeds.
FAQs:
Can Sunixar 12.5mg Capsule cause changes in skin color? Yes, can cause changes in skin color. One common side effect is called "hand-foot syndrome," which can cause redness, swelling, and pain in the palms of the hands and soles of the feet. This syndrome can sometimes cause the skin to darken or become thickened in these areas.
Can Sunixar 12.5mg Capsules cause heart problems? Yes, can cause heart problems such as high blood pressure, heart failure, and heart attack.
Can Sunixar 12.5mg Capsule cause kidney problems? Yes, can cause kidney problems such as proteinuria (excess protein in the urine) and renal impairment.
Can I take Sunixar 12.5mg Capsule if I have a thyroid problem? Yes, but your healthcare provider will monitor your thyroid function regularly.
Can Sunixar 12.5mg Capsule affect fertility? Yes, can affect fertility in both men and women.
How can Sunixar 12.5mg Capsule affect my blood? Can cause hematologic toxicity, which may include neutropenia (low white blood cell count), thrombocytopenia (low platelet count), and anemia (low red blood cell count).