Active ingredient: Sunitinib
Classification: Tyrosine kinase inhibitor
Mechanism of action: Blocks certain enzymes called tyrosine kinases involved in the growth and spread of cancer cells.
Uses:
- Renal cell carcinoma (RCC)
- Gastrointestinal stromal tumors (GIST)
- Pancreatic neuroendocrine tumors (PNET)
- Medullary thyroid cancer
- Certain kidney cancer
Important information:
- Not recommended for people under 18.
- Discuss with physician if you have blood conditions, heart problems, liver disorders, kidney problems, skin disorders, diabetes, seizures, or thyroid disorders.
- Inform if you have recently had or are about to have surgery.
- Avoid taking grapefruit in any form during treatment.
- Check with dentist before starting treatment if you have any mouth problems.
Storage:
- Store at room temperature, between 68°F and 77°F (20°C and 50°C).
- Keep in the original package.
- Protect from moisture, light, and heat.
- Keep out of reach from children and pets.
How to consume:
- Taken orally, in the form of capsules, with a glass of water.
- Swallow whole, do not crush, chew, or open.
- Recommended dose may vary depending on the type of cancer being treated, the patient's age and weight, and other factors.
- Usually taken once a day, with or without food, at around the same time each day.
- If you miss a dose, do not double the dose to compensate.
Safety advices:
- Pregnancy: Unsafe for a developing fetus, not recommended.
- Breast feeding: Discuss potential risks and benefits with healthcare provider.
- Lungs: Can cause interstitial lung disease, monitor for symptoms.
- Liver: Can cause liver toxicity, monitor liver function tests regularly.
- Alcohol: Avoid consuming alcohol during treatment.
- Driving: Avoid driving or operating machinery if experiencing side effects such as fatigue, dizziness, or blurred vision.
Side effects:
- Serious: Heart failure or heart attack, elevated liver function tests, liver failure, proteinuria, acute kidney injury, interstitial lung disease, pulmonary arterial hypertension, gastrointestinal perforation or fistula, haemorrhage, hypothyroidism, hypoglycemia.
- Common: Fatigue, nausea and vomiting, diarrhoea, loss of appetite, hand-foot syndrome, skin discoloration or rash, high blood pressure, headache, hair loss, changes in taste, dry skin or itching, nosebleeds.
FAQs:
Can Sugistran 12.5mg Capsule cause changes in skin color? Yes, can cause changes in skin color, including hand-foot syndrome and other skin changes.
Can Sugistran 12.5mg Capsules cause heart problems? Yes, can cause heart problems such as high blood pressure, heart failure, and heart attack.
Can Sugistran 12.5mg Capsule cause kidney problems? Yes, can cause kidney problems such as proteinuria and renal impairment.
Can I take Sugistran 12.5mg Capsule if I have a thyroid problem? Yes, but healthcare provider will monitor thyroid function regularly.
Can Sugistran 12.5mg Capsule affect fertility? Yes, can affect fertility in both men and women.
How can Sugistran 12.5mg Capsule affect my blood? Can cause hematologic toxicity, including neutropenia, thrombocytopenia, and anemia.