Trelegy Ellipta inhaler is a combination of three active drugs Fluticasone Furoate + Umeclidinium + Vilanterol. It is used to treat chronic obstructive pulmonary disease (COPD) symptoms such as wheezing, shortness of breath, coughing, and chest tightness in adults. It is also indicated to reduce the worsening of COPD in patients with a history of severe breathing symptoms. Fluticasone belongs to the group of drugs known as Corticosteroids. Umeclidinium is in a class of medication called anticholinergics. Vilanterol belongs to a group of drugs known as long-acting beta-agonists (LABAs). The combination of fluticasone, umeclidinium, and vilanterol eases breathing by relaxing and opening airways in the lungs.
Trelegy Ellipta Inhaler comes as a powder to inhale by mouth using an inhaler. This medicine should be used regularly as per your doctor's advice. Do not use this if you are allergic to Fluticasone Furoate+Umeclidinium+Vilanterol or any of the other ingredients of this medicine. Inform your doctor if you have any heart, liver, or respiratory problems before starting the treatment. Report to the physician immediately if you have any symptoms of pneumonia or other respiratory disorders after using this medicine. This medicine is not recommended for children or adolescents below the age of 18 years.
The most frequent adverse effect of the Trelegy Ellipta inhaler is common cold. Along with this, you could also experience headaches, a cough, a clogged nose, a fungal infection of the mouth, and an infection of the nose. Inform your doctor if any of these adverse effects last longer than expected or develop worse.
Uses of Trelegy Ellipta Inhaler
Therapeutic Effects of Trelegy Ellipta Inhaler
The Trelegy Ellipta inhaler contains fluticasone furoate, a corticosteroid, umeclidinium, an anticholinergic, and vilanterol, a long-acting beta(2)-agonist. Fluticasone furoate inhibits pro-inflammatory signaling molecules by activating the steroid response element and prevents lung airway inflammation brought on by exposure to antigens. Umeclidinium inhibits certain receptors in the smooth muscles of the airway, leading to the dilation of bronchi and bronchioles. Vilanterol increases certain messenger levels in our body, which causes the bronchial smooth muscles to relax.
Interaction of Trelegy Ellipta Inhaler with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, or herbal products you take or have taken before the treatment. Certain medications containing CYP3A4 inhibitors may interact with the Trelegy Ellipta inhaler and cause undesirable side effects.
More Information about Trelegy Ellipta Inhaler
How to consume Trelegy Ellipta Inhaler
Your doctor will tell you how much medicine to use. Do not use more than directed. Use this medicine at the same time each day.
- Trelegy Ellipta inhaler is a powder that is used with its own inhaler device. Keep the medicine in the foil tray until you are ready to use the inhaler.
- Each time you open the cover of the inhaler and hear a click, the inhaler is ready to use. Do not close the cover until you have taken your dose. You will lose the dose if you open and close the cover without inhaling the medicine.
- To inhale this medicine, breathe out fully and put the mouthpiece between your lips, and close your lips firmly around it. Take one long, steady, deep breath in through your mouth. Do not breathe in through your nose. Do not block the air vent with your fingers.
- Remove the inhaler from your mouth and hold your breath for about 3 to 4 seconds, then breathe out slowly.
- When you have finished inhaling, rinse your mouth out with water. Do not swallow the water.
- You may clean the mouthpiece using a dry tissue, if needed, before closing the cover.
Safety Advices for Trelegy Ellipta Inhaler
Pregnancy
There is limited data regarding using Trelegy Ellipta inhaler in pregnant women to determine a drug-associated risk. If you are pregnant or think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. Do not use this medicine if you are pregnant unless your doctor tells you to take it.
Breast Feeding
It is unknown whether Trelegy Ellipta inhaler are excreted in human milk. Ask your doctor for advice before taking this medicine. Do not use this medicine if you are breastfeeding or planning to breastfeed unless your doctor tells you to take it.
Lungs
Talk to your doctor before using the Trelegy Ellipta inhaler if you have liver problems.
Liver
Talk to your doctor before using the Trelegy Ellipta inhaler if you have liver problems.
Alcohol
It is not known whether it is safe to consume alcohol with the Trelegy Ellipta inhaler. Please consult your doctor.
Driving
It is unlikely that Trelegy Ellipta inhaler will affect your ability to drive or use machines. Please consult your doctor for more advice.
Side Effects of Trelegy Ellipta Inhaler
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common:
- Cough
- Common cold and upper respiratory infections
- Sore throat
- Diarrhea
- Headache
- Back pain
- Urinary tract infections
- Influenza
Serious:
- Increased heart rate
- Increased blood sugar levels
- Decreased potassium levels
- Hypersensitivity reaction
- Fungal infections
- Decreased bone mineral density
- Cataract, glaucoma
- Severe respiratory problems
Word of Advice
Use Trelegy Ellipta inhaler exactly as prescribed by your doctor. Follow the usage instructions correctly. Do not take more than one inhalation per day. Inform your doctor if you are pregnant, breastfeeding or if you have liver disease, heart disease, asthma, high blood pressure, heart rhythm problems, thyroid problems, or a history of eye problems. Tell your doctor right away if your condition gets worse. Your doctor may check your progress and the effects of this medicine at regular visits.
FAQs
Q 1. What if I forget to take the Trelegy Ellipta inhaler?
If you miss a dose of the Trelegy Ellipta inhaler, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and return to your regular schedule. Do not double the dose.
Q 2. What should I tell my doctor before using the Trelegy Ellipta inhaler?
Inform your doctor if you are pregnant, breastfeeding or if you have liver disease, heart disease, asthma, high blood pressure, heart rhythm problems, thyroid problems, or a history of eye problems. Also, inform if you are allergic to milk proteins.
Q 3. Should I stop taking Trelegy Ellipta inhaler if my COPD symptoms improve?
Do not stop taking Trelegy Ellipta inhaler unless told to do so by your healthcare provider because your symptoms may get worse.
Q 4. How do I know I have received the dose?
After you slide the cover down to expose the mouthpiece, you will hear a “click,” and the dose counter will decrease by 1 count. Even if when using the Trelegy Ellipta inhaler correctly, you may not taste or feel the medicine, and you should not take another dose.
Q 5. What do the 30 means in the dose counter?
Each Trelegy Ellipta inhaler contains 30 doses, which equals a 30-day supply. That’s why your dose counter starts at 30 and reduces by 1 count with each inhaled dose.
Q 6. How to use Trelegy Ellipta inhaler?
Trelegy Ellipta inhaler is a powder that is used with its own inhaler device. Keep the medicine in the foil tray until you are ready to use the inhaler. Each time you open the cover of the inhaler and hear a click, the inhaler is ready to use. Do not close the cover until you have taken your dose. You will lose the dose if you open and close the cover without inhaling the medicine. To inhale this medicine, breathe out fully and put the mouthpiece between your lips, and close your lips firmly around it. Take one long, steady, deep breath in through your mouth. Do not breathe in through your nose or block the air vent with your fingers. Remove the inhaler from your mouth and hold your breath for about 3 to 4 seconds, then breathe out slowly. When you have finished inhaling, rinse your mouth out with water.
Fact Box of Trelegy Ellipta Inhaler
Molecule name: Fluticasone Furoate + Umeclidinium + Vilanterol | Therapeutic class: 1. Fluticasone furoate - Corticosteroids 2. Umeclidinium - Anticholinergics 3. Vilanterol - Long-acting-beta-agonists |
Pharmacological class: Anticholinergics; Beta2 Agonists; Corticosteroids; Inhalants; Respiratory Inhalant Combos. | Indications: To treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema. |