Rybrevant 350mg Injection
Uses:
- Treatment of non-small cell lung cancer (NSCLC) that has spread to other parts of the body and has certain changes in the EGFR gene.
- Used when the cancer cannot be removed by surgery and has worsened during or after treatment with other anticancer medications.
Active substance:
- Amivantamab, a bispecific antibody.
Important information:
- Do not take if allergic to amivantamab or any other ingredients of this medicine.
- Inform your physician if you have suffered from inflammation of your lungs or any other lung conditions before initiating the therapy.
- Not recommended for children or young people below 18 years of age.
- Inform your physician if you have kidney, liver, or lung problems before initiating the therapy.
Common side effects:
- Rash
- Nail inflammation
- Musculoskeletal pain
- Shortness of breath
- Nausea
- Fatigue
- Swelling
- Inflamed and sore mouth
- Cough
- Constipation
- Vomiting
Serious side effects:
- Severe rashes in the skin
- Eye pain and infection
- Inflammation of the lungs
- Infusion reactions
Safety advice:
- Pregnancy: unsafe to administer in pregnant women. Use effective contraception during treatment and for 3 months after the last dose.
- Breastfeeding: not recommended in patients taking Rybrevant 350mg injection.
- Lungs: consult your doctor if you have any lung diseases before starting the treatment.
- Liver: consult your doctor if you have any liver problems before starting the treatment.
- Alcohol: it is unknown whether consuming alcohol is safe during the treatment with Rybrevant 350mg injection.
- Driving: Rybrevant 350mg injection does not affect the ability to drive, but if you feel tired or dizzy after taking this medicine, do not drive and consult your doctor for more advice.
How to consume:
- Administered by a doctor or nurse in a hospital or clinic setting.
- Given as an intravenous infusion drip (into your vein) for several hours.
- Do not self-administer the injection.
- Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.
Storage:
- Store in the refrigerator (2°C to 8°C).
- Do not freeze.
- Keep away from the reach of children and pets.
FAQ:
Q: What are the infusion reactions that might happen during Rybrevant 350mg infusion? A: Allergic reactions like itching, swelling in your face or hands, tingling in mouth or throat, chest tightness, difficulty in breathing, fever, chills, cough, sore throat, body aches, unusual bleeding, bruising, or weakness. Inform your doctor immediately.
Q: How long should I have to take Rybrevant 350mg injection? A: Rybrevant 350mg injection is given as a cycle therapy. Your doctor will decide the dose and duration of the therapy based on your disease severity and condition.
Q: How long does Rybrevant 350mg infusion take? A: Your first dose (the infusion on Day 1 and Day 2) can take about 4 to 6 hours. Infusions can get shorter starting on Week 2, and can take about 2 to 4 hours. Your doctor will decide the infusion rate based on your disease condition and other factors.
Q: What are the eye problems that may occur while taking Rybrevant 350mg injection? A: Eye pain, dry eyes, eye redness, blurred vision, changes in the vision, itchy eyes, excessive tearing, sensitivity to light. Inform your physician if you face any of the symptoms.
Q: Why should I avoid sun exposure during the treatment with Rybrevant 350mg injection? A: Rybrevant 350mg injection can cause skin reactions. You should limit your time in the sun during your treatment with this medicine.
Q: Can I take vitamin supplements with Rybrevant 350mg injection? A: Certain medications may interact with the effectiveness of Rybrevant 350mg injection including prescription, over-the-counter medicines, vitamin or nutritional supplements and herbal products. Inform your physician about all your medication history.
Fact box:
- Molecule name: Amivantamab
- Therapeutic class: Antineoplastics
- Pharmacological class: EGFR inhibitor & MET tyrosine kinase inhibitors
- Indications: Treat non-small cell lung cancer (NSCLC)