Granulomatosis with polyangiitis or microscopic polyangiitis;
Pemphigus vulgaris.
Mechanism of action:
Reditux RA 500mg injection is a monoclonal antibody that targets the antigen CD20 expressed on the cell surface of B-lymphocytes.
When the medicine binds to the B-cell, it induces cell death in NHL and CLL.
It inhibits rheumatoid factor production, antigen presentation, T-cell activation, and proinflammatory cytokine production in rheumatoid arthritis.
Important information:
Do not take this injection if you are allergic to rituximab or any other ingredients of this medicine, have a weak immune system, or have any severe active infection.
Inform your physician if you have heart disease, heart failure, or breathing problems before initiating the treatment.
Talk with your doctor if you have ever had a hepatitis B infection.
Pregnancy and breastfeeding are not recommended when you are taking this injection.
Side effects:
Common side effects include infection of the blood, reduced red blood cells, dizziness, swelling in the face and body, itchy skin, diarrhea, increased sweating, and low or high blood pressure.
Serious side effects include increased or decreased blood pressure, chest pain, hypersensitivity reactions, hepatitis B viral infection, memory loss, trouble thinking, difficulty in walking.
Interaction with other drugs:
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products.
Certain medications may interact with Reditux RA 500mg injection and reduce its effectiveness by causing undesirable side effects.
Storage:
Store Reditux RA 500mg injection in the refrigerator (2°C to 8°C).
Do not freeze.
Keep the injection away from the reach of children and pets.
Administration:
It should only be administered by a trained doctor or nurse.
Do not self-administer the injection.
Before giving Reditux RA 500mg injection, you will be given other medications (pre-medication) to reduce the possible side effects.
Your doctor will decide the dose and duration of your treatment based on the disease severity and other factors.
Safety advice:
Pregnancy: Reditux RA 500mg injection is unsafe to administer in pregnant women because it may affect the fetus.
Breastfeeding: Breastfeeding is not recommended in patients taking Reditux RA 500mg injection.
Lungs: Consult your doctor if you have any lung diseases before starting the treatment.
Liver: Consult your doctor if you have or ever had liver disease or hepatitis B infection before starting the treatment.
Alcohol: Stop consuming alcohol if you are taking this medicine.
Driving: Caution is required while driving and operating machinery when you take Reditux RA 500mg injection because it may cause dizziness, sleepiness, tiredness, and risk of falling.
FAQs:
What are the special precautions I should be aware of before starting treatment with Reditux RA 500mg injection?
Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.
What are Reditux RA 500mg infusion-related reactions?
Infusion reactions occur during or within 24 hours after administering Reditux RA 500mg injection. The symptoms are fever, chills, cough, itchy skin, nausea, vomiting, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.
What will be the most important thing to monitor during Reditux RA 500mg injection?
Your healthcare professional will monitor you carefully for unwanted side effects during the Reditux RA 500mg injection. You will be monitored for heart failure, increased blood pressure, or breathing failure.
Is weight gain a side effect of Reditux RA 500mg injection?
Weight gain has been reported in patients treated with Reditux RA 500mg injection for non-Hodgkin’s lymphoma.
Does Reditux RA 500mg injection suppress the immune system?
Yes, it can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking Reditux RA 500mg injection because it may cause drug-induced immunosuppression.
