Targeted therapy containing pertuzumab and trastuzumab.
Used to treat human epidermal growth factor receptor 2 positive breast cancer that has spread to other parts of the body or cancer that has come back after treatment.
Can also be given before or after surgery if the cancer has not metastasized.
Uses:
Breast cancer.
Non-small cell lung cancer.
Therapeutic Effects:
Binds selectively to the HER2 receptors on breast cancer cells' surface.
Blocks them from receiving growth signals.
Stops the cancer cells' growth.
Interaction with Other Drugs:
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products.
Certain medications may interact with Phesgo 1200mg/600mg Injection and reduce effectiveness by causing undesirable side effects.
Storage:
Store in a refrigerator between 2°C and 8°C (36°F and 46°F).
Do not freeze.
Keep it in its original packaging until it is ready to be used.
Keep out of the reach of children and pets.
Administration:
Administered intravenously (IV) by a healthcare professional.
Follow the healthcare provider's instructions regarding the dosage and administration of medication.
Do not double the dose to make up for missed doses.
Safety Advices:
Pregnancy: may harm the developing fetus, so it is unsafe to use it during pregnancy.
Breastfeeding: it is unknown whether Phesgo 1200mg/600mg Injection is excreted in human milk. Breastfeeding women should consult their doctor before taking it.
Lungs: can cause side effects, and the safety of their use in the lungs depends on several factors. Patients should consult their doctor if they have any pre-existing health condition before taking this medication.
Liver: patients with pre-existing liver disease or impaired liver function may be at increased risk for the potential side effects of Phesgo 1200mg/600mg Injection, including liver toxicity.
Alcohol: alcohol use can negatively affect the immune system, and patients receiving Phesgo 1200mg/600mg Injection may already have compromised immune systems. Therefore, it is generally recommended that patients limit their alcohol consumption or avoid alcohol entirely while receiving it.
Driving: patients should always monitor their response to the Phesgo 1200mg/600mg Injection medication and be cautious when driving or operating machinery if they experience any side effects that may impair their ability to do so safely.
Side Effects:
Serious: pulmonary toxicity, infusion-related reactions, hypersensitivity reactions, liver toxicity, immune system effects, severe allergic reactions, gastrointestinal perforation (rare), reduced blood platelets or white blood cell counts.
Common: nausea and vomiting, diarrhea, fatigue, hair loss, rash or itching, muscle pain or weakness, headache, difficulty sleeping, loss of appetite.
Word of Advice:
Carefully read and understand the warnings and precautions associated with the medication.
Patients should be monitored for signs of an allergic reaction, such as rash, itching, or swelling, and should seek immediate medical attention if these symptoms occur.
Use with caution in patients with severe renal impairment.
Talk to the physician if you have heart problems, have had radiotherapy, or have allergic conditions.
Use effective birth control during the treatment and at least seven months after the last dose.
Maintain a healthy and balanced diet to support your overall health and well-being.
FAQs:
Can Phesgo 1200mg/600mg Injection cause infertility?
Phesgo 1200mg/600mg Injection can affect fertility in some patients, although the extent of this effect is not well-understood. Women who wish to preserve their fertility should discuss their options with their healthcare provider before starting treatment with these drugs.
Can Phesgo 1200mg/600mg Injection be used together with chemotherapy?
Yes, Phesgo 1200mg/600mg Injection are often combined with chemotherapy to treat HER2-positive breast cancer. This combination therapy effectively reduces the risk of recurrence and improves overall survival in patients with HER2-positive breast cancer.
Can I take Phesgo 1200mg/600mg Injection if I have TB?
If you have active tuberculosis (TB) infection, Phesgo 1200mg/600mg Injection should not be used until the TB infection has been treated and is under control. These drugs can suppress the immune system, worsening TB or other infections.
Can Phesgo 1200mg/600mg Injection cause skin reactions?
Yes, Phesgo 1200mg/600mg Injection can cause skin reactions, including rash, dry skin, and itching. In some cases, these skin reactions can be severe and require treatment. Patients should promptly report any new or worsening skin symptoms to their healthcare provider.
Can Phesgo 1200mg/600mg Injection affect blood counts?
Yes, Phesgo 1200mg/600mg Injection can affect blood counts and may increase the risk of anemia, thrombocytopenia, and neutropenia. These blood disorders can cause symptoms such as fatigue, weakness, and an increased risk of infections or bleeding. Patients receiving this medication should check their blood counts regularly.
Can Phesgo 1200mg/600mg Injection be used in older adults?
Yes, Phesgo 1200mg/600mg Injection can be used in older adults. However, older adults may be at increased risk of side effects like heart-related complications or infections. Healthcare providers may need to adjust the dose or monitor more closely for potential side effects in older patients.
Can Phesgo 1200mg/600mg Injection be used in men with breast cancer?
Yes, Phesgo 1200mg/600mg Injection can be used in men with HER2-positive breast cancer. Breast cancer is rare in men, accounting for less than 1% of all breast cancer cases. However, HER2-positive breast cancer is more common in men than in women with breast cancer.
