Pazotab 400mg Tablet
Active substance: Pazopanib
Class: Antineoplastic drug, Tyrosine kinase inhibitor
Uses:
- Advanced renal cell carcinoma
- Advanced soft tissue sarcoma
Mechanism of action:
- Pazotab 400mg Tablet interferes with the growth of blood vessels inside cancer cells by acting against a protein called Vascular Endothelial Growth Factors (VEGF).
- This helps to shrink cancer cells, stopping their growth and multiplication.
Important information:
- Do not take if you are allergic to Pazopanib or any other ingredients of this medicine.
- Inform your physician if you have kidney, heart, lung, or liver problems, bleeding disorders, stomach or bowel problems, and thyroid problems.
- Your doctor will advise you to stop Pazotab 400mg Tablet at least 7 days before any surgeries or dental operations.
- This medicine is not recommended for people aged under 18.
- Consult your doctor before taking this medicine if you are planning to become pregnant or are breastfeeding.
Dosage and administration:
- Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors.
- Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water.
- Take Pazotab 400mg Tablet at least two hours after a meal or one hour before a meal.
- Do not take this medicine with food, as it affects the absorption of this medicine.
Safety advice:
- Pregnancy: Pazotab 400mg Tablet is unsafe to administer in pregnant women because it may affect the fetus.
- Breastfeeding: Breastfeeding is not recommended in patients taking Pazotab 400mg Tablet because the medicine passes into the breast milk in small amounts and may harm your baby.
- Lungs: It is unknown whether Pazotab 400mg Tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
- Liver: Pazotab 400mg Tablet is unsafe when administered in patients with severe liver diseases. Dose adjustments are necessary for moderate liver failure.
- Alcohol: It is unknown whether it is safe to consume alcohol when taking Pazotab 400mg Tablet. Consult your doctor for more advice.
- Driving: Driving or operating heavy machinery is unsafe after taking Pazotab 400mg Tablet because you may feel dizzy, drowsy, or have blurred vision.
Side effects:
- Common: Hypertension, hair color change, increased glucose levels, decreased weight, decreased appetite, diarrhea, nausea, vomiting, muscle and joint pain, headache, shortness of breath, tiredness.
- Serious: Heart problems, bleeding from the anus, mouth, hypothyroidism, interstitial lung disease, infections.
FAQs:
What if I forgot to take Pazotab 400mg tablet? If you forgot to take a dose, take it as soon as you remember. However, skip the missed dose if it is nearly time for the next dose. Do not take a double dose to make up the forgotten dose.
Can Pazotab 400mg tablet induce liver toxicity? Yes, long-term use of Pazotab 400mg tablet may induce liver toxicity or severe liver failure. Inform your physician if you have any liver disorders before starting treatment with this medicine. Your doctor may advise you to take certain blood tests to check your liver function periodically.
Does Pazotab 400mg tablet change hair color? Hair color change is a common side effect of Pazotab 400mg tablet therapy which usually develops gradually during a few months of therapy. Consult your doctor for more advice.
Is anemia a side effect of Pazotab 400mg tablet? Pazotab 400mg tablet can reduce the number of red blood cells, which transport oxygen throughout the body. A low number of red blood cells is called anemia. This may make you feel tired and short of breath. Tell your doctor or nurse if you have these symptoms.
What are the benefits of Pazotab 400mg tablet? Pazotab 400mg tablet is used to treat certain types of cancer (kidney, soft tissue sarcoma). It decreases the blood supply to the cancer tumor to slow tumor growth.
Storage:
- Store Pazotab 400mg Tablet in room temperature (25°C).
- Keep the medicine away from the reach of children and pets.