Class of medication: Immunosuppressant, calcineurin inhibitor
Uses:
Treatment of moderate to severe atopic dermatitis (eczema) in adults who cannot use other medications or whose eczema has not responded to other treatments.
Important information:
Do not use if you are allergic to tacrolimus or any other ingredients of this medicine.
Inform your doctor if you have liver failure, skin problems, skin cancer, or a weakened immune system.
Report any allergic reactions to antibiotics to your physician.
Seek immediate medical attention if you experience fever, bruising under the skin, unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, or seizures.
Precautions:
Limit exposure to sunlight and UV light by wearing appropriate protective clothing and sunscreen with a high sun protection factor.
Do not apply the ointment to infected areas.
Consult your physician immediately if you notice any changes in your skin.
This medicine is not approved for children younger than 16 years of age.
Interaction with other drugs:
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, vaccinations, nutritional and vitamin supplements, and herbal products.
Avoid grapefruit or grapefruit juice while taking this medicine.
Storage:
Store Pangraf 0.03% Ointment at 25°C.
Keep the ointment away from the reach of children and pets.
How to use:
Use Pangraf 0.03% Ointment exactly as advised by your doctor.
Apply a thin layer to the affected areas of your skin.
Avoid using the ointment inside your nose, mouth, or eyes.
Before using the ointment, ensure your skin is completely dry.
If you forget to apply the ointment at the scheduled time, do it as soon as you remember. If it is almost time for the application, skip the missed dose.
Do not apply more quantity than advised.
Safety advice:
Pregnancy: Based on animal studies, Pangraf 0.03% Ointment can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant before initiating the treatment.
Breastfeeding: Do not use Pangraf 0.03% Ointment if you are breastfeeding because this medicine is excreted into breast milk and may cause harmful effects on the body.
Lungs: It is unknown whether Pangraf 0.03% Ointment can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver: Pangraf 0.03% Ointment should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your doctor if you have liver problems before initiating the therapy.
Alcohol: It is unsafe to consume alcohol when taking Pangraf 0.03% Ointment because it may cause the skin or face to become flushed or red and feel hot.
Driving: It is unknown whether Pangraf 0.03% Ointment can impair the ability to drive. Consult your doctor for more advice.
Side effects:
Common: Burning sensation and itching, redness, feeling or warmth, pain, increased skin sensitivity to hot and cold, skin tingling, rash.
Serious: Acne, facial redness, eye infections, lentigo (flat brown spots on the skin), cold sores, swelling of the hands, arms, feet, ankles, or lower legs.
Word of advice:
You may use moisturizing creams and lotions during the treatment with this ointment but remember that these products should not be used within two hours of applying Pangraf 0.03% Ointment.
Do not eat grapefruit or drink grapefruit juice while you are using tacrolimus.
Do not drink alcohol while you are using this medicine.
This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines.
Apply sunscreen with a good SPF and wear protective clothing before you step out in the sun.
Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.
FAQs:
What is Pangraf 0.03% Ointment used for?
Pangraf 0.03% Ointment is indicated to treat moderate to severe atopic dermatitis. Atopic Dermatitis is a skin condition where the immune system reacts excessively, leading to inflammation (itching, redness, and irritation).
Who should not use Pangraf 0.03% Ointment?
Children below the age of 2 years and people who have experienced hypersensitivity to Tacrolimus or macrolide antibiotics should not use Pangraf 0.03% Ointment. Pangraf 0.03% Ointment 0.1% W/W is not recommended for children below the age of 16 years.
Can you consume alcohol during treatment with Pangraf 0.03% Ointment?
Drinking alcohol while on treatment with Pangraf 0.03% Ointment may lead to flushing, redness, and heat sensation in the face and skin. Hence, alcohol consumption is not recommended.
What should you not use with Pangraf 0.03% Ointment?
Inform your healthcare provider you are taking or have taken oral corticosteroids, immunosuppressants, moisturizers, or other cosmetics before starting treatment with Pangraf 0.03% Ointment. Ensure you don’t apply moisturizing lotions or creams within two hours of applying Pangraf 0.03% Ointment.
What should you avoid while using Pangraf 0.03% Ointment?
Avoid sun exposure, as Pangraf 0.03% Ointment makes your skin sensitive. Wear protective clothing and use an effective sunscreen to prevent skin damage from sun exposure. Do not go near smoke or flame after applying Pangraf 0.03% Ointment.
How long does Pangraf 0.03% Ointment take to work?
Pangraf 0.03% Ointment shows improvement on the skin within one week of application. Discuss alternative treatment with your healthcare provider if you do not notice any changes within two weeks of starting the treatment.
Should I follow any dietary restrictions while taking Pangraf 0.03% Ointment?
Pangraf 0.03% Ointment can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of tacrolimus in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.
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