Nintenib 100mg Capsule
Active ingredient: Nintedanib
Therapeutic class: Antifibrotic drug
Pharmacological class: Tyrosine kinase inhibitors
Uses:
- Idiopathic pulmonary fibrosis;
- Chronic fibrosing interstitial lung disease with a progressive phenotype;
- Systemic sclerosis-associated interstitial lung disease.
Mechanism of action: Nintenib 100mg works by inhibiting receptor multiple tyrosine kinases (RTKs) enzyme that develops and progresses lung fibrosis (scarring). Inhibiting these enzymes reduces the development of fibrous tissue in the lungs.
Important safety information:
- Consult your physician if you are on blood thinning medications or have recently undergone surgery.
- Use effective contraception while receiving this capsule and continue to use it for three months, even after receiving the final dose.
- Inform your doctor if you have any medical conditions, such as liver and heart problems.
- Before starting the treatment, your doctor may conduct a liver function test at regular intervals during the first three months.
- Notify your doctor if you have a history of bleeding or blood clots (arterial thromboembolic).
Side effects:
- Serious: bronchitis, myocardial infarction, bleeding problems, pneumonia, major bleeding, yellow eyes, dark urine, pain in the upper right side of the stomach, severe stomach cramps, bloating, fever, and chills, chest pressure or pain on the left side of the body, increased protein in the urine (proteinuria).
- Common: nausea, vomiting, diarrhea, fever, skin ulcer, gastrointestinal perforation, altered liver function values, decreased appetite, headache, weight loss, hypertension.
Interaction with other drugs: Inform your healthcare professional about all the medicines you take, including prescription, over-the-counter, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Nintenib 100mg and reduce its effectiveness or cause undesirable side effects.
Storage: Store at room temperature of 20°C to 25°C. Protect from light and moisture. Keep out of reach and sight of children and pets.
Dosage and administration: Take Nintenib 100mg as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking this medicine unless your doctor advises you to stop.
Pregnancy and breastfeeding: Nintenib 100mg is unsafe to use during pregnancy as it may cause birth defects or death to the unborn baby. Taking Nintenib 100mg while breastfeeding may be unsafe because it may affect the child. Therefore, talk with your doctor to get more information.
FAQs:
How does Nintenib 100mg work in the body? Nintenib 100mg works by inhibiting several signaling pathways involved in the formation of scar tissue in the lungs.
Can Nintenib 100mg cure idiopathic pulmonary fibrosis (IPF)? This medicine is not a cure for idiopathic pulmonary fibrosis (IPF). It is a medication that can help slow the progression of the disease by reducing the formation of scar tissue in the lungs.
How can I manage diarrhea while taking Nintenib 100mg? If you experience diarrhea while taking Nintenib 100mg, staying hydrated by drinking plenty of fluids is important. Your doctor may also recommend over-the-counter medications or prescription medications to help manage your diarrhea.
Can Nintenib 100mg cause liver damage? Nintedanib may cause liver function abnormalities, which may indicate liver damage. It is important to have regular blood tests to monitor your liver function while taking Nintenib 100mg.
What dosage of Nintenib 100mg should I take? Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking Nintenib 100mg unless your doctor advises you to stop.
Why is liver enzyme getting elevated during treatment with Nintenib 100mg? The reason for this elevation is not completely understood, but it is thought to be related to the drug's effects on certain enzymes involved in liver function. The elevation in liver enzymes is generally mild and temporary and typically resolves on its own or with dose adjustment of the Nintenib 100mg capsule.