Uses:
- Idiopathic pulmonary fibrosis.
- Chronic fibrosing lung diseases with a progressive phenotype.
- Systemic sclerosis.
Therapeutic effects: Nintena 150mg works by inhibiting receptor multiple tyrosine kinases (RTKs) enzyme that develops and progresses lung fibrosis (scarring). Inhibiting these enzymes reduces the development of fibrous tissue in the lungs.
Interaction with other drugs: Inform your healthcare professional about all the medicines you take, including prescription, over-the-counter, nutritional and vitamin supplements, and herbal products. Certain medications include a P-glycoprotein (P-gp), CYP3A4 inhibitor, Ketoconazole, Anticoagulants, St. John’s wort, Laxatives, and other drugs, interacting with Nintena 150mg may reduce effectiveness by causing undesirable side effects.
Safety advice:
- Pregnancy: Nintena 150mg is unsafe to use during pregnancy as it may cause birth defects or death to the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment.
- Breastfeeding: Taking Nintena 150mg while breastfeeding may be unsafe because it may affect the child. Therefore, talk with your doctor to get more information.
- Lungs: Consult your doctor if you experience symptoms like pneumonia or any other lung related condition while taking Nintena 150mg.
- Liver: Inform your physician if you have liver problems because Nintena 150mg should be used cautiously with this condition. Before starting treatment, your physician conducts the liver function test regularly for the first three months.
- Alcohol: It is unknown whether consuming alcohol while taking a Nintena 150mg capsule is safe. Please speak with your physician.
- Driving: While taking Nintena 150mg, driving or using machines is unsafe because it may cause nausea, changes in vision, vomiting, etc. Talk to your doctor for more information.
Side effects:
- Serious: bronchitis, myocardial infarction, bleeding problems, pneumonia, major bleeding, yellow eyes, dark urine, pain in the upper right side of the stomach, severe stomach cramps, bloating, fever, and chills, chest pressure or pain on the left side of the body, increased protein in the urine (proteinuria).
- Common: nausea, vomiting, diarrhea, fever, skin ulcer, gastrointestinal perforation, altered liver function values, decreased appetite, headache, weight loss, hypertension.
Word of advice:
- Inform your physician if you have bleeding problems, hypertension, heart problems or weak blood vessels.
- Inform your physician if you experience allergic reactions to Nintena 150mg.
- Notify your physician if you have recently undergone a surgery as this medicine affects the process of wound healing.
- Consult your physician and use an effective method of contraception while on this treatment and even after the treatment for three months.
- Abnormalities, such as dark or brown urine, bruises, bleeding than usual, or jaundice, must be notified immediately to your doctor.
- Avoid smoking while taking Nintena 150mg because it may reduce the effectiveness of the medicine.
FAQs:
How does Nintena 150mg work in the body? Nintena 150mg Nintedanib works by inhibiting several signaling pathways involved in the formation of scar tissue in the lungs. It targets the activity of certain enzymes and growth factors that promote the growth of fibroblasts, which are the cells responsible for producing collagen and other proteins that form scar tissue in the lungs.
Can Nintena 150mg cure idiopathic pulmonary fibrosis (IPF)? Nintena 150mg is not a cure for idiopathic pulmonary fibrosis (IPF). It is a medication that can help slow the progression of the disease by reducing the formation of scar tissue in the lungs. It is important to continue taking Nintena 150mg as your doctor prescribes, even if you start feeling better.
How can I manage diarrhea while taking Nintena 150mg? If you experience diarrhea while taking Nintena 150mg, staying hydrated by drinking plenty of fluids is important. Your doctor may also recommend over-the-counter medications or prescription medications to help manage your diarrhea. If your diarrhea is severe or persistent, you should contact your doctor.
Can Nintena 150mg cause liver damage? Nintena 150mg may cause liver function abnormalities, indicating liver damage. It is important to have regular blood tests to monitor your liver function while taking Nintena 150mg. If you experience symptoms of liver damage, such as jaundice or abdominal pain, you should contact your doctor immediately.
What dosage of Nintena 150mg should I take? Your doctor will decide the correct dose and duration based on your age, body weight, and disease condition. Do not stop taking Nintena 150mg unless your doctor advises you to stop.
Why is liver enzyme getting elevated during treatment with Nintena 150mg? The reason for this elevation is not completely understood, but it is thought to be related to the drug's effects on certain enzymes involved in liver function. The elevation in liver enzymes is generally mild and temporary and typically resolves on its own or with dose adjustment of the Nintena 150mg capsule.
Fact box:
- Molecule name: Nintedanib.
- Therapeutic class: Antifibrotic drug.
- Pharmacological class: Tyrosine Kinase inhibitors.