Contains the active substance propofol, which belongs to a class of medicines called general anesthetics.
Used to cause partial or complete reversible loss of consciousness (in adults and children over the age of 1 month) for surgical procedures.
Can also be used to induce sleep in patients (16 years or older) receiving artificial respiration in an Intensive Care Unit (ICU).
Uses:
Reversible loss of consciousness (general anesthesia).
Therapeutic Effects:
Produces loss of consciousness by potentiating the actions of certain brain chemicals (neurotransmitter GABA) through the specific receptors (ligand-gated GABA A receptors) and decreasing the flow of chloride ions across the nerve cells required to maintain alertness.
Interaction with Other Drugs:
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment.
Certain medications may interact with Neorof 10ml injection and cause undesirable side effects, especially if you are taking the antibiotic rifampicin (for tuberculosis-TB).
Safety Advice:
Pregnancy: Neorof 10ml can pass the placental barrier and cause miscarriage, birth defects, or neonatal depression during pregnancy. Consult your doctor for advice before taking this medicine.
Breastfeeding: Neorof 10ml can be excreted into human breast milk and lead to neonatal depression if used during breastfeeding. Consult your doctor to determine when it's safe to resume breastfeeding while undergoing this medication.
Lungs: Neorof 10ml injection is used with caution for severe breathing disorders. Inform your doctor if you have any active lung disease.
Liver: Neorof 10ml injection can cause enlargement of the liver very rarely. Inform your doctor if you have mild/moderate/severe liver problems before taking this medication.
Alcohol: Drinking alcohol while using Neorof 10ml injection can make the sedation even stronger. It is not recommended to have alcohol unless your doctor says it is okay after the effect of the medicine has worn off.
Driving: Neorof 10ml can affect your ability to drive and handle heavy machinery, so it is not recommended to drive until told by your doctor that the sleepy effect of the injection is gone.
Side Effects:
Serious: allergic reactions (difficulty in breathing, swelling of the eyelids, face, or lips, rash or itching), stress cardiomyopathy (chest pain, shortness of breath, nausea, or an irregular heartbeat).
Common: injection site pain, low blood pressure, changes in your breathing pattern, slow heartbeat, nausea and vomiting, headache, withdrawal symptoms (unusual behavior, sweating, shaking, and feeling anxious in children), flushing of the skin (in children).
Word of Advice:
Inform your doctor if you are on a sodium-controlled diet or have allergies to peanuts or soya, as Neorof 10ml injection contains these components.
If the injection is administered over extended periods in intensive care, your doctor may prescribe a zinc supplement to prevent a decrease in your zinc levels.
It is essential to trust your medical team and communicate openly with them.
FAQs:
How long does the effect of Neorof 10ml injection last?
The effect of Neorof 10ml injection typically lasts for 24 hours, but this can vary from person to person, depending on the administered dose.
Is Neorof 10ml injection indicated for children?
Neorof 10ml is not recommended to maintain anesthesia in children under one month.
What should I take before getting my Neorof 10ml injection?
Adults and teenagers over 12 can eat solid foods and dairy products up to 8 hours before their hospital arrival time. Avoid alcohol within 8 hours of your appointment. You can have clear liquids, not dairy, up to 2 hours before surgery to stay hydrated.
What restrictions should I follow after a Neorof 10ml injection?
It's important to avoid alcohol consumption during the treatment, as it may intensify the sedative effect. Additionally, do not operate a vehicle or heavy machinery since it causes severe drowsiness or dizziness, which may last several hours after the treatment.
Can Neorof 10ml injection cause dependence?
As a sedative agent, Neorof 10ml injection can potentially increase dependence and be subject to abuse. It is strictly not meant for self-administration and should only be administered by a healthcare provider. When used beyond the therapeutic dose, it can be life-threatening.
Can Neorof 10ml be taken orally?
No, Neorof 10ml is typically administered as an injection because most of it is processed by the liver when taken by mouth. So, the usual method for receiving Neorof 10ml is through an intravenous (IV) injection (into your veins) administered by a trained anesthesiologist.
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