Systemic mastocytosis with associated hematological neoplasm (SM-AHN)
Mast cell leukemia (MCL)
Important Information
Contraindications: Do not take Midostar 25mg capsule if you are allergic to Midostaurin or any other ingredients of this medicine.
Warnings: Inform your healthcare professional if you have any symptoms of an infection, heart disorder, lung problems, or problems with breathing.
Pregnancy and Breastfeeding: Midostar 25mg capsule is unsafe to administer in pregnant women because it may cause birth defects. Breastfeeding is not recommended in patients taking Midostar 25mg capsule.
Liver: Midostar 25mg capsule should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure.
Alcohol: It is unsafe to consume alcohol when taking Midostar 25mg capsule because it may cause alcohol-related problems, epilepsy, or liver problems.
Driving: Driving vehicles or operating machinery after taking Midostar 25mg capsule is unsafe as you may develop dizziness and vertigo.
Dosage and Administration
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors.
Take the Midostar 25mg capsule as prescribed by your doctor. Do not open, break, crush, or chew the capsules. Swallow the capsule whole with a glass of water.
Take the capsules with food at the same time each day.
Side Effects
Common: Swelling in the lower limbs, skin rash, increased blood sugar levels, abdominal pain, constipation, diarrhea, nausea, vomiting, musculoskeletal pain, headache, bleeding from nose, upper respiratory infection, tiredness, fever.
Serious: Heart failure, GI bleeding, fever with decreased blood cell counts, hypersensitivity reactions, kidney problems, pneumonia, blood infection.
Safety Advice
Avoid grapefruit juice during the treatment with this medicine.
If you vomit after taking this medicine, do not take another capsule to make up the dose.
Your doctor will perform regular blood tests during the treatment to monitor the number of blood cells and electrolytes in your body.
Your heart and lung function will also be checked regularly.
FAQs
Q 1. What are the cautions of Midostar 25mg capsule? Tell your doctor immediately if you start to have swelling of your face, lower limbs or skin, fever, sore throat, mouth ulcers, cough with or without mucous, chest pain or discomfort, trouble breathing, shortness of breath, light-headedness, fainting, dizziness, blue discoloration of your lips, hands or feet.
Q 2. Can Midostar 25mg capsule cause vomiting? Yes, Midostar 25mg capsule has a moderate emetic effect and can cause vomiting. Do not take an extra capsule if you have vomited after taking your first dose.
Q 3. Does Midostar 25mg capsule cause hair loss? No, hair loss is not a side effect of Midostar 25mg capsule. Hair loss can happen due to cancer itself. Consult your doctor if you have excessive hair loss.
Q 4. How will I be monitored during the treatment with Midostar 25mg capsule? Your doctor will perform regular blood tests during treatment with Midostar 25mg capsule in order to monitor the number of blood cells (white blood cells, red blood cells, and platelets) and electrolytes such as calcium, potassium, and magnesium in your body. Your heart and lung function will also be checked regularly.
Q 5. How long does it take Midostar 25mg capsule to work? Midostar 25mg capsule is a long-term treatment. Most people who benefit from this treatment will notice an improvement in the first 12 weeks of starting treatment.
Q 6. What will happen if I stop taking Midostar 25mg capsule suddenly? Stopping your treatment suddenly may cause your condition to become worse. Do not stop taking your medicine without consulting your doctor.