Lenava 10mg Capsule belongs to the group of medicines known as Immunomodulatory agents. It contains the active ingredient Lenalidomide. It is indicated to treat adults with multiple myeloma, mantle cell lymphoma, myelodysplastic syndrome and follicular lymphoma. Multiple myeloma refers to the cancerous progression of plasma cells that are predominant in the bone marrow. These cells gather in the bone marrow and split uncontrollably. This type of cancer cannot be cured; however, the symptoms can be alleviated. Myelodysplastic Syndrome is a group of various blood and bone marrow diseases, where the blood cells become abnormal and do not function properly. Mantle cell lymphoma is a less common type of cancer that affects the lymph nodes. Follicular lymphoma is a slow-growing cancer that affects the B cells.
The common side effects that are likely to be associated with Lenava 10mg Capsule are nausea, diarrhea, constipation, muscle cramps, tiredness, fever, cough, headache, tiredness, back pain, breathlessness, rashes, thyroid and skin problems. Inform your doctor if any of these side effects disturb or persist in you.
Inform your doctor if you have allergic reactions to Lenava 10mg Capsule and its ingredients. Before taking treatment with this medication, let your physician know if you ever had blood clots, heart attack or if you smoke or have high blood pressure and cholesterol level. Inform your physician if you have viral infections like hepatitis B infection, varicella zoster, HIV. Before and during treatment with this medication your healthcare provider will take regular blood test because it may cause fall in blood cells. It is not recommended for children below 18.
Uses of Lenava 10mg Capsule
Therapeutic Effects of Lenava 10mg Capsule
Lenava 10mg Capsule activates T cells and natural killer cells of the immune system and facilitates the attack on cancer cells. It works by antagonizing the growth of blood vessels in the cancer cells and delays the development of cancer cells. It inhibits growth and multiplication of tumor cells.
Interaction of Lenava 10mg Capsule with other drugs
Inform your doctor about any prescribed medicines, over-the-counter medications, nutritional and vitamin supplements, or herbal products that you are taking or have taken before the treatment. Certain medications may interact with Lenava 10mg Capsule and cause undesirable side effects.
More Information about Lenava 10mg Capsule
How to consume Lenava 10mg Capsule
Swallow the capsule whole with water. This capsule shall be consumed with or without food. Avoid crushing, chewing or breaking them.
Safety Advices for Lenava 10mg Capsule
Pregnancy
Lenava 10mg Capsule is unsafe to use during pregnancy as it might be harmful to an unborn child. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.
Breast Feeding
Lenava 10mg Capsule is probably unsafe to use during breastfeeding as it is not known if this medication passes into breast milk and harms your baby.
Lungs
Inform your physician before taking Lenava 10mg Capsule if you have if you have any lung conditions.
Liver
Inform your physician before starting treatment with Lenava 10mg Capsule if you have severe liver problems including liver failure. Your physician will do blood tests to monitor your liver function.
Alcohol
It is not known whether it is safe to consume alcohol while taking Lenava 10mg Capsule. Consult your doctor for advice.
Driving
Do not drive or operate machines if you feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Lenava 10mg Capsule.
Side Effects of Lenava 10mg Capsule
Side Effects:
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Severe allergic reactions
- High risk of secondary cancer
- Liver toxicity
- Blurred vision
- Difficulty speaking
- Faster heartbeat
- Chest pain or leg pain
- Swelling in the ankles
- Dizziness
- Unusual bleeding or bruising
- Blood clot formation
Common:
- Tiredness
- Neutropenia
- Constipation
- Diarrhea
- Muscle cramps
- Anaemia
- Fever
- Back pain
- Nausea
- Upper respiratory tract infection
- Breathlessness
- Tremor
- Rash
- Cough
- Headache
- Thyroid problems
- Dehydration
- Skin problems
Word of Advice
Male patients are advised to use effective contraception (condom) during treatment with Lenava 10mg Capsule and for 7 days at the end of the treatment even though if you have undergone vasectomy. They should not donate sperm because this medication is present in the semen. It is advised not to donate blood during therapy and for at least 7 days after treatment.
FAQs
Q 1. What class of medication is Lenava 10mg Capsule?
Lenava 10mg Capsule belongs to the class of medication known as immunomodulatory agents.
Q 2. Is it safe to donate blood while taking Lenava 10mg Capsule?
When taking Lenava 10mg Capsule, patients are prohibited from donating blood while receiving treatment and for 7 days after the end of treatment. Because, donated blood may be given to pregnant mothers that may cause serious birth abnormalities.
Q 3. May I take Lenava 10mg Capsule on an empty stomach?
You can take Lenava 10mg Capsule with or without food. Take it precisely as your doctor has advised. Ever chew, cut, or crush the capsules.
Q 4. What is the best time to take Lenava 10mg Capsule?
Lenava 10mg Capsule can be taken at any time of the day but it is best to take it at approximately the same time each day.
Q 5. Does Lenava 10mg Capsule make you tired?
Yes, Tiredness (fatigue) is the common side effect of Lenava 10mg Capsule. Consult with your doctor if any of the side effects disturbs you.
Fact Box of Lenava 10mg Capsule
Molecule name: Lenalidomide | Therapeutic class: Immunomodulatory agents |
Pharmacological class: Antineoplastics | Indications: 1. Treatment of multiple myeloma, myelodysplastic syndrome 2. Treatment of mantle cell lymphoma 3. Treatment of follicular lymphoma |
References
1. H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
2. Bristol-Myers Squibb Pharma EEIG, Electronic Medicines Compendium (EMC), [Revised on Nov 2020] [Accessed on 23 Nov 2022], https://www.medicines.org.uk/emc/files/pil.10046.pdf
3. Celgene Corporation, US Food & Drug Administration, [Revised on Jun 2013] [Accessed on 23 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021880s034lbl.pdf
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