Darb-ESA 40mcg injection is an antineoplastic medication that belongs to a class of drugs known as hematopoietic growth factors. It contains the active compound Darbepoetin Alfa . It is used to treat anemia in people with chronic kidney disease. and anemia caused by chemotherapy in people with certain types of cancer.
It is not recommended to take Darbepoetin alfa if you are allergic to active compounds or any other ingredients of this medicine. It is recommended to monitor complete blood count before starting the therapy. It is not recommended for use in patients who have uncontrolled blood pressure. It is not recommended for use in patients who receive cancer treatment with hormonal drugs and radiotherapy. It is not advised to be used in place of red blood cell transfusions in individuals in need of immediate anemia correction. Inform your physician if you have high blood pressure, anemia, a history of seizures, epilepsy, liver disease, or allergy to latex or hepatitis C. Inform your physician if you are pregnant or breastfeeding.
Before initiating the treatment, inform your physician if you have fever, blood clots, any infections, kidney, heart or liver problems. Your doctor will monitor your haemoglobin levels to ensure they stay within a specified range. High haemoglobin concentrations can increase your chance of developing heart or blood vessel problems. It is necessary to inform your physician about all the medicines, over the counter drugs, vitamin and herbal supplements you are taking before the start of therapy.
Uses of Darb-esa 40mcg InjectionTo treat anemia in chronic kidney failureTo treat anemia caused by chemotherapy Therapeutic Effects of Darb-esa 40mcg Injection
Darb-ESA 40mcg injection is an erythropoiesis-stimulating protein produced by recombinant DNA technology. The erythropoietin receptor on the surface of erythroid progenitor cells in the bone marrow is bound by Darb-ESA 40mcg injection and activated. This activation sets off a signaling cascade that increases the erythroid progenitor cells' ability to survive, proliferate, and differentiate, ultimately increasing the generation of red blood cells. Interaction of Darb-esa 40mcg Injection with other drugsInform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Darb-ESA 40mcg injection and reduce effectiveness by causing undesirable side effects.More Information about Darb-esa 40mcg Injection Store in a refrigerator (2°C to 8°C).Do not freeze.Store in the original package to protect from light.Keep the injection away from the reach of children and pets.It should be kept dry and protected from light and moisture.It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.How to consume Darb-esa 40mcg InjectionThe injection is to be administered subcutaneously, or beneath the skin. Your doctor will provide you instruction on how to use this pre-filled pen for self-injection. If you are not well-trained, do not attempt to inject the pre-filled pens. Never put the medication intravenously. Visit the hospital or clinic in the area if you require assistance administering the medication.The dosage and frequency of Darb-ESA 40mcg injection will depend on various factors, including the patient's age, weight, overall health and condition being treated. It's important to follow the dosing instructions provided by a healthcare provider, and not to adjust the dosage or frequency without consulting with them first.
If a dose is missed, it should be taken as soon as possible unless it's within 6 hours of the next scheduled dose. In that case, the missed dose should be skipped and the regular dosing schedule resumed.
Safety Advices for Darb-esa 40mcg Injection
Pregnancy
There are no adequate and well-controlled studies on the use of Darb-ESA 40mcg injection in pregnant women. Inform your physician if you are pregnant, suspecting, or planning for pregnancy during the treatment.
Breast Feeding
Darb-ESA 40mcg injection is not recommended during breastfeeding, as it is unknown if Abemaciclib is excreted in human milk. Because of the potential risk to the infant, breastfeeding is not recommended.
Lungs
It is unknown whether Darb-ESA 40mcg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Dose adjustments are necessary for patients with liver disorders. Inform your physician if you have any liver diseases or problems before initiating the therapy.
Alcohol
It is typically advised that patients taking Darb-ESA 40mcg injection avoid or consume alcohol in moderation since it can worsen any liver-related adverse effects and raise the risk of liver damage.
Driving
Darb-ESA 40mcg injection will not make you feel tired, dizzy, or sleepy. It is safe to drive or operate heavy machinery after taking this medicine.
Side Effects of Darb-esa 40mcg InjectionSide effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.Common
- Swelling in the face and body
- Low blood pressure
- Abdominal pain
- Shortness of breath
- cough
Serious
- Heart problems
- Severe skin reactions
- Anemia
- Seizure attack
- Lung problems
Word of AdviceYou will be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to. Do not shake the vial or syringe. You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. You should stay well-hydrated, maintain a healthy diet rich in iron and other nutrients, and avoid activities that may increase your risk of injury or bleeding. It is recommended to monitor your blood counts at regular intervals. Eat less foods that contain high-sodium such as packaged snacks, canned soups, processed meats, and fast food, as too much salt can cause hypertension and fluid retention. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately.FAQs Q 1. Can Darb-ESA 40mcg injection be used in patients with kidney failure who are undergoing dialysis?Yes, Darb-ESA 40mcg injection is commonly used in patients with kidney failure who are undergoing dialysis to manage anemia.
Q 2. Can Darb-ESA 40mcg injection be used in patients with a history of heart disease?Darb-ESA 40mcg injection should be used with caution in patients with a history of heart disease, as it may increase the risk of certain cardiovascular events. It is crucial to discuss the potential risks and benefits with a healthcare provider before initiating treatment.
Q 3. Can Darb-ESA 40mcg injection be used to treat anemia caused by nutritional deficiencies?Darb-ESA 40mcg injection is not typically used to treat anemia caused by nutritional deficiencies. It is primarily used for anemia related to chronic kidney disease, cancer chemotherapy, and other specific conditions. Nutritional deficiencies require appropriate dietary changes and/or supplementation.
Q 4. Can Darb-ESA 40mcg injection be used to treat anemia in patients undergoing radiation therapy?Darb-ESA 40mcg injection is used to treat anemia in patients undergoing chemotherapy, depending on the specific circumstances and the healthcare provider's recommendation. The anemia is typically managed through a comprehensive treatment plan determined by the oncology team.
Q 5. Can Darb-ESA 40mcg injection interact with other medications?Darb-ESA 40mcg injection may interact with certain medications, such as blood thinners or immunosuppressants. It is important to inform the healthcare provider about all medications, including over-the-counter drugs and supplements, to avoid potential interactions or adverse effects.
Fact Box of Darb-esa 40mcg InjectionMolecule name: Darbepoetin alfa | Therapeutic class: Antineoplastics |
Pharmacological class: Hematopoietic growth factors | Indications: 1. To treat anemia in chronic kidney failure 2. To treat anemia caused by chemotherapy |
Dosage form: Injection | Habit forming: No |
