Invega Sustenna 150mg Injection: Long-acting Antipsychotic for Stable Patients

Invega Sustenna 150mg Injection

Active component: Paliperidone.

Therapeutic class: Antipsychotic Agents.

Pharmacological class: Atypical Antipsychotic Agents.

Uses:

• Treatment of schizophrenia;
• Treatment of schizoaffective disorder.

Mechanism of action:

• Paliperidone works by affecting certain neurotransmitters in the brain, specifically dopamine and serotonin, which regulate mood, behavior, and cognition.
• Reduces excessive dopamine activity to alleviate the positive symptoms of schizophrenia.
• Modulates serotonin receptors to manage both positive and negative symptoms.

Contraindications:

• Known allergy to Invega Sustenna 150mg Injection or other antipsychotic medications;
• Severe hypersensitivity reactions to other antipsychotic medications from the same class;
• Cardiovascular disease;
• Seizures;
• Certain medical conditions.

Precautions:

• Discuss your complete medical history with your healthcare provider before starting this medication;
• Dosage adjustments may be necessary in patients with renal impairment;
• Use cautiously in patients with a history of cardiovascular disease, seizures, or certain medical conditions;
• Store at room temperature, between 20°C to 25°C (68°F to 77°F);
• Keep away from moisture, heat, and light;
• Do not freeze;
• Keep away from children and pets.

Administration:

• Administered through extended-release injection;
• Administered by a healthcare professional as a monthly injection, gradually releasing the medication over time.

Safety advice:

• Pregnancy: discuss with a healthcare professional;
• Breastfeeding: discuss with a healthcare professional;
• Respiratory conditions: individuals with pre-existing respiratory conditions should inform their healthcare provider before starting the medication;
• Liver impairment: individuals with liver impairment should consult a healthcare provider before using the medication;
• Alcohol consumption: avoid alcohol or use it in moderation;
• Driving: may cause drowsiness, dizziness, or other side effects that can affect your ability to drive or operate machinery safely.

Side effects:

• Serious: extrapyramidal symptoms, neuroleptic malignant syndrome (NMS), tardive dyskinesia, cardiovascular effects, metabolic changes, blood disorders, seizures;
• Common: drowsiness or sedation, dizziness, weight gain, increased heart rate, dry mouth, constipation.

FAQs:

1. Can I stop taking Invega Sustenna 150mg Injection suddenly? No, sudden discontinuation can lead to withdrawal symptoms or symptom recurrence. Consult your doctor before making any changes to your medication regimen.
2. What should I do if I miss a dose? Take it as soon as you remember. However, if it's close to the time for the next dose, skip the missed dose and continue with your regular schedule.
3. Can Invega Sustenna 150mg Injection be crushed or split? Invega Sustenna 150mg Injection tablets should not be crushed, split, or chewed unless your healthcare provider advises. Follow their instructions for proper administration.
4. What should I do if I accidentally take an extra dose of Invega Sustenna 150mg Injection? Contact your healthcare provider or seek medical advice for guidance.
5. Can I drink grapefruit juice while taking Invega Sustenna 150mg Injection? Avoiding large amounts of grapefruit juice while on Invega Sustenna 150mg Injection is generally advisable, as it may interact with the medication's metabolism.
6. Can side effects of Invega Sustenna 150mg Injection impact my mental health? Some side effects, such as changes in mood or cognition, can impact mental health. Discuss any concerns with your healthcare provider promptly.

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