Non-small cell lung cancer (has not spread outside your chest).
Small cell lung cancer (has spread within your lungs).
Biliary tract cancers (cancer of the bile ducts).
How it works:
Imfinzi 120mg Injection contains the active ingredient Durvalumab, which belongs to the class of Anti-PD-1 monoclonal antibodies.
It works by blocking a protein called programmed death-ligand 1 (PD-L1), which is found on the surface of certain cancer cells.
By blocking the interaction between PD-L1 and its receptor, this drug allows T cells to recognize and attack cancer cells more effectively.
Important information:
This medicine is not recommended for adolescents and children under the age of 18.
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products.
Store Imfinzi 120mg injection in the refrigerator at (2°C to 8°C). Do not freeze. Keep it out of reach from children.
Dosage and administration:
Imfinzi 120mg injection is a prescription drug available in injection form.
This injection will be given intravenously into a vein in your arm or hand by a healthcare professional in a hospital setting.
Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors.
During the infusion, you will be monitored for any side effects or reactions to the medication.
Safety advice:
Pregnancy: Imfinzi 120mg injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Breastfeeding: It is not known if Imfinzi 120mg injection passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.
Lungs: Consult your doctor if you have any lung diseases before starting the treatment.
Liver: Inform your doctor if you have any liver problems before taking Imfinzi 120mg injection. Regular monitoring of liver function tests is recommended.
Alcohol: It is unknown whether consuming alcohol interacts with Imfinzi 120mg injection. Please consult your doctor for more advice.
Driving: It is unsafe to drive vehicles or operate heavy machinery after taking Imfinzi 120mg injection, it may cause dizziness and impair your concentration.
Side effects:
Serious: infection (chills, increased temperature), serious lung infections (pneumonia), fungal infection in the mouth, tooth and mouth soft tissue infections, flu-like illness, overactive thyroid gland that can cause fast heart rate or weight loss, inflammation of the lungs (pneumonitis), hoarse voice (dysphonia), abnormal liver tests (aspartate aminotransferase increased; alanine aminotransferase increased), night sweats, muscle pain (myalgia), abnormal kidney function tests (blood creatinine increased), painful urination, swelling of the legs (oedema peripheral), reaction to the infusion of the medicine that can cause fever or flushing.
Common: cough, upper respiratory tract infections, feeling tired, shortness of breath, inflammation in the lungs, rash.
FAQs:
How will I receive Imfinzi 120mg injection?
Imfinzi 120mg injection is administered intravenously into a vein in your arm or hand by a healthcare professional.
How does Imfinzi 120mg injection work?
It works by blocking a protein called programmed death-ligand 1 (PD-L1), which is found on the surface of certain cancer cells. When PD-L1 binds to its receptor on T cells, it can inhibit the immune system's ability to recognize and attack cancer cells. By blocking the interaction between PD-L1 and its receptor, this medicine allows T cells to recognize and attack cancer cells more effectively.
Can Imfinzi 120mg injection be used in combination with other drugs?
Yes, Imfinzi 120mg injection is often used in combination with other immunotherapy drugs, such as tremelimumab, to boost the immune response against cancer cells.
Is Imfinzi 120mg injection safe to use during pregnancy?
Imfinzi 120mg injection is not recommended during pregnancy and it is unsafe because it may harm a developing fetus. Women who are pregnant or planning to become pregnant should discuss their treatment options with their doctor immediately.
Who should not take Imfinzi 120mg injection?
This drug is not recommended in patients with autoimmune diseases, such as lupus, rheumatoid arthritis, or multiple sclerosis, who may be at an increased risk of side effects from Imfinzi 120mg injection, and it should be used with caution in these patients.