Glivec 400mg Tablet: Effective Treatment for Chronic Myeloid Leukemia

Glivec 400mg Tablet

Active substance: Imatinib

Class: Tyrosine kinase inhibitor

Indications:

• Chronic myeloid leukemia (CML)
• Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL)
• Gastrointestinal stromal tumors (GIST)
• Myelodysplastic/myeloproliferative diseases (MDS/MPD)
• Hypereosinophilic syndrome (HES)
• Chronic eosinophilic leukemia (CEL)
• Dermatofibrosarcoma protuberans (DFSP)

Usage:

• Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water.
• Take this medicine with a meal to avoid stomach problems.
• If you are unable to swallow the tablets, you can dissolve them as per your doctor's advice.

Contraindications:

• Do not take Glivec 400mg tablet if you are allergic to imatinib or any other ingredients of this medicine.
• Inform your physician if you have kidney, heart, or liver problems, thyroid problems, or if your thyroid gland has been removed.
• Notify your doctor if you ever had or have a hepatitis B infection.

Safety advice:

• Pregnancy: Glivec 400mg tablet is unsafe to administer in pregnant women because it may affect the fetus.
• Breastfeeding: Breastfeeding is not recommended in patients taking Glivec 400mg tablet.
• Lungs: Consult your doctor if you have any lung diseases before starting the treatment.
• Liver: Glivec 400mg tablet is unsafe when administered in patients with severe liver diseases.
• Alcohol: It is unknown whether it is safe to consume alcohol when taking Glivec 400mg tablet. Consult your doctor for more advice.
• Driving: It is unsafe to drive or operate heavy machinery after taking Glivec 400mg tablet.

Side effects:

• Common: swelling in the face, legs, ankle, and feet; nausea, vomiting; muscle cramps and pain; diarrhea; skin rash, night sweats; tiredness, dizziness; abdominal pain; increased weight; decreased RBC and WBC cells; headache; cough, inflammation in the nose; fever, lack of sleep.
• Serious: heart failure; GI disorders; hypothyroidism; liver failure; swelling in the body.

FAQ:

1. How to use Glivec 400mg tablet?

   • Glivec 400mg tablet is administered orally, in the form of a tablet or capsule, and the dose depends on several factors, including the condition being treated, the weight of the patient, the particular regimen being used, and the overall health of the patient. It should be taken with food and a large glass of water to minimize gastrointestinal irritation.

2. Ever since I started using Glivec 400mg tablet, I have noticed rashes and severe itching when I have sun exposure. Is it because of the medicine or the disease?

   • This medicine may make your skin much more sensitive to sunlight than it normally is. Exposure to sunlight may cause skin rash, itching, redness, or severe sunburn. When you are outdoors, wear protective clothing and use sunscreen with an SPF. Consult your doctor before taking necessary precautions.

3. Can Glivec 400mg tablet cause kidney damage?

   • Yes, when taken for a longer period, the medicine may cause damage to your kidneys. Your doctors may recommend you take a routine blood tests to assess your kidney function.

4. When is the best time to take Glivec 400mg tablet?

   • Take the tablet as prescribed by your doctor. Take Glivec 400mg tablet at the same time every day. It is usually taken with a meal and a large glass of water to avoid stomach problems.

5. Does Glivec 400mg tablet affect memory?

   • Memory impairments have been only reported in limited studies. Consult your doctor immediately if you have any trouble in concentrating.

Storage:

• Store Glivec 400mg tablet in room temperature (25°C).
• Keep the injection away from the reach of children and pets.
• If you forgot to take a dose, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose.
• Do not take a double dose to make up for a forgotten dose.
• Avoid direct contact with crushed tablets with the skin or mucous membrane. If such contact occurs, wash thoroughly.

Tags: cancer_treatment, imatinib, pharmaceuticals, medicine, drugs, oncology, 400mg, tablet