To prevent infections after chemotherapy due to decreased white blood cells (neutropenia).
In people undergoing bone marrow transplants.
In people with severe chronic neutropenia (low number of neutrophils in the blood).
To prepare the blood for leukapheresis (a treatment in which certain blood cells are removed from the blood).
To increase the chance of survival in people exposed to harmful amounts of radiation.
In patients with advanced HIV infection to reduce the risk of infections.
Therapeutic Effects:
Frastim 300mcg injection is a colony-stimulating factor that acts on blood-forming cells by binding to specific cell surface receptors, thereby inducing cell division, multiplication, and cell functional activation.
Interaction with other drugs:
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Frastim 300mcg injection and reduce effectiveness by causing undesirable side effects.
Storage and administration:
Store Frastim 300mcg injection in a refrigerator (2°C – 8°C). Do not freeze.
Do not shake the pre-filled syringe.
Discard the medicine if stored at room temperature for more than 48 hours.
Keep it out of reach from children and pets.
It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor immediately for advice.
Frastim 300mcg injection is available as a prefilled syringe. A qualified healthcare professional will administer the injection in the fatty tissues just under your skin (subcutaneously) or it will be administered as an intravenous injection into your vein slowly. The dose, route of administration, and frequency will be decided by your doctor based on your disease condition and other factors.
Safety Advices:
Pregnancy: Frastim 300mcg injection is unsafe when administered during pregnancy because it may cause birth defects in your baby. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Breastfeeding: It is unsafe to breastfeed during the treatment with this Frastim 300mcg injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Lungs: It is unknown whether Frastim 300mcg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Liver: It is unknown whether Frastim 300mcg injection can be administered in patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this Injection.
Alcohol: It is unsafe to consume alcohol with Frastim 300mcg injection. Please consult your doctor for more advice.
Driving: It is unsafe to travel, drive vehicles, or operate heavy machinery after taking (1 hour) Frastim 300mcg injection. Please consult your doctor.
Side Effects:
Common: pain in the bones, joints, and muscles; pain at the site of injection; fever; itchiness and skin rash; nausea; headaches; dizziness and tiredness; nose bleeding; hair fall.
Serious: inflammation of aorta; capillary leak syndrome (plasma leaks out of tiny blood vessels); hypersensitivity reactions; changes in urine color; swelling in hands, feet, face, and abdomen; difficulty in breathing; sickle cell anemia.
Word of Advice:
Inform your physician if you are experiencing any symptoms of swelling in the face, feet, hands, and abdomen, difficulty in breathing, sudden drop in blood pressure, left abdominal pain, weakness, and skin rashes.
Read the package insert carefully if you are self-administering the medicine.
This medicine may cause lung, liver, or kidney problems. Your physician may advise you to take laboratory tests regularly to monitor the effectiveness of the therapy.
FAQs:
What are the symptoms that I should notify the physician while taking Frastim 300mcg injection?
Inform your physician if you are experiencing any symptoms of swelling in the face, feet, hands, and abdomen, difficulty in breathing, sudden drop in blood pressure, left abdominal pain, weakness, and skin rashes.
What is the Frastim 300mcg injection package insert?
The FDA provides a package insert, which summarizes the relevant scientific information needed for healthcare practitioners and patients to use the drug safely and effectively. The package insert contains safety information, instruction for use, and other information.
Who should not take Frastim 300mcg injection?
Frastim 300mcg injection is not indicated for everyone. Do not take this medicine if you are allergic to any forms of rubber, latex, pegfilgrastim, filgrastim or any of the other ingredients in this medicine.
Will Frastim 300mcg injection affect my kidneys?
This medicine may affect your kidneys. Regular kidney function tests will be taken to monitor your kidney functions. Inform your physician if you have any kidney problems.
Can I breastfeed while taking Frastim 300mcg injection?
No, this medicine secretes in small amounts in breast milk. Frastim 300mcg injection can cause harm to your baby. Please consult your doctor if you are breastfeeding.
