Enfiera 100mg Injection
Uses:
- Non-Hodgkin’s lymphoma (NHL);
- Chronic lymphocytic leukemia (CLL);
- Rheumatoid arthritis;
- Granulomatosis with polyangiitis or microscopic polyangiitis;
- Pemphigus vulgaris.
Therapeutic effects:
- Enfiera 100mg injection is a monoclonal antibody that targets the antigen CD20 expressed on the cell surface of B-lymphocytes. It induces cell death in NHL and CLL.
- In rheumatoid arthritis, it inhibits rheumatoid factor production, antigen presentation, T-cell activation, and proinflammatory cytokine production.
Interaction with other drugs:
- Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products.
- Certain medications may interact with Enfiera 100mg injection and reduce its effectiveness by causing undesirable side effects.
Safety advice:
- Pregnancy: Enfiera 100mg injection is unsafe to administer in pregnant women because it may affect the fetus.
- Breastfeeding: Breastfeeding is not recommended in patients taking Enfiera 100mg injection.
- Lungs: Consult your doctor if you have any lung diseases before starting the treatment.
- Liver: Consult your doctor if you have or ever had liver disease or hepatitis B infection before starting the treatment.
- Alcohol: Stop consuming alcohol if you are taking this medicine.
- Driving: Caution is required while driving and operating machinery when you take Enfiera 100mg injection.
Side effects:
- Common: swelling in the face and body, diarrhea and nausea, itchy skin, anemia, muscle spasm, headache, urinary tract infection, fever, chills, and shivering, inflammation of nasal cavities, cough, sore throat, loss of hair.
- Serious: increased or decreased blood pressure, chest pain, hypersensitivity reactions, hepatitis B viral infection, memory loss, trouble thinking, difficulty in walking.
FAQ:
Q 1. What are the special precautions I should be aware of before starting treatment with Enfiera 100mg injection? A: Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.
Q 2. What are Enfiera 100mg infusion-related reactions? A: Infusion reactions occur during or within 24 hours after administering Enfiera 100mg injection. The symptoms are fever, chills, cough, itchy skin, nausea, vomiting, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.
Q 3. What will be the most important thing to monitor during Enfiera 100mg injection? A: Your healthcare professional will monitor you carefully for unwanted side effects during the Enfiera 100mg injection. You will be monitored for heart failure, increased blood pressure, or breathing failure.
Q 4. Is weight gain a side effect of Enfiera 100mg injection? A: Weight gain has been reported in patients treated with Enfiera 100mg injection for non-Hodgkin’s lymphoma.
Q 5. Does Enfiera 100mg injection suppress the immune system? A: Yes, Enfiera 100mg injection can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking Enfiera 100mg injection.
Fact box:
- Molecule name: Rituximab;
- Therapeutic class: Antineoplastics, DMARDs;
- Pharmacological class: Anti-CD20 monoclonal antibodies;
- Indications: Non-Hodgkin’s lymphoma, chronic lymphocytic leukemia (CLL), rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis, pemphigus vulgaris.