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₹2 333

Endobloc 5mg Tablet

Brand: CIPLA LTD
Product Code: MRM_201109
Reviews: (0)
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₹2 333
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Specifications: (see all)
Manufacturer
CIPLA LTD
Origin of Medicine
India
Price for
10 Tablet(s) In A Strip
Salt Composition
Ambrisentan
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Endobloc 5mg tablet contains an active component as Ambrisentan. This medication is used to treat pulmonary arterial hypertension (PAH). PAH is a condition characterized by high blood pressure in the arteries that carry blood from the heart to the lungs. It helps to relax and widen the blood vessels in the lungs, reducing the strain on the heart and improving blood flow. It is typically prescribed as a long-term treatment for PAH to improve exercise capacity and delay disease progression. By targeting the underlying mechanisms of PAH, this medication can slow down the progression of the disease. This can result in a longer period of better health and quality of life for individuals with PAH. Endobloc 5mg tablet can be used as a monotherapy (used alone) or in combination with other PAH medications, depending on the severity of the condition and the patient's response to treatment. In general, it is considered well-tolerated by most patients. While there can be side effects, they are usually manageable, and healthcare providers can monitor and adjust treatment accordingly.

If an individual has a known allergy or hypersensitivity to Endobloc 5mg tablet or its components, its use should be avoided. Inform your healthcare provider about any pre-existing medical conditions, such as gastrointestinal disorders, liver disease, kidney disease, or other health conditions. These may require special precautions or adjustments in the use of this medication. This medication can sometimes lead to fluid retention, and worsening heart failure symptoms in some individuals. People with a history of heart failure require close monitoring while taking the medication. There have been reports of decreases in red blood cell counts (anemia) and decreases in white blood cell counts while taking Endobloc 5mg tablet. Regular blood tests are required during the treatment. Grapefruit juice can increase the levels of this medication in the body, which could potentially lead to an increased risk of side effects. Therefore, consuming grapefruit juice should be avoided while taking this medication.

Uses of Endobloc 5mg TabletEndobloc 5mg tablet is used to treat the following:

  • Pulmonary arterial hypertension

Therapeutic Effects of Endobloc 5mg Tablet

Endobloc 5mg tablet is an endothelin receptor antagonist that exerts its therapeutic effect by selectively blocking the effects of endothelin, a substance that causes blood vessels to constrict and tighten. By inhibiting endothelin's action, this medication promotes vasodilation (widening of blood vessels) in the pulmonary arteries, reducing the resistance to blood flow and lowering pulmonary arterial pressure. This mechanism of action improves blood flow to the lungs, lessens the strain on the right side of the heart, and ultimately enhances exercise capacity and quality of life in individuals with pulmonary arterial hypertension (PAH).

Interaction of Endobloc 5mg Tablet with other drugsInform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications including birth control pills and medications that affect liver enzymes may interact with Endobloc 5mg tablet, reducing effectiveness by causing undesirable side effects. 

More Information about Endobloc 5mg Tablet
  • Store at room temperature, between 20°C to 25°C (68°F to 77°F).
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.
  • How to consume Endobloc 5mg TabletEndobloc 5mg tablet is usually taken orally once daily, with or without food. It's important to follow the prescribed dosage provided by your healthcare provider and to take the medication at the same time each day to maintain consistent levels in your system. Swallow the tablet whole with water and do not crush or chew it. 

    Safety Advices for Endobloc 5mg Tablet

      

    Pregnancy

      

    Endobloc 5mg tablet is known to cause serious birth defects and is contraindicated during pregnancy.

      

    Breast Feeding

      

    It is unknown if Endobloc 5mg tablet passes into breast milk. Because of the potential for harm to the infant, women should avoid breastfeeding while taking it.

      

    Lungs

      

    Endobloc 5mg tablet is primarily used to treat pulmonary arterial hypertension (PAH). It's important to inform your healthcare provider about any lung conditions you have, as they will need to assess whether the benefits of the medication outweigh any potential risks.

      

    Liver

      

    Endobloc 5mg tablet is primarily metabolized by the liver. Individuals with severe liver impairment should not take this medication. Regular liver function tests are typically recommended to monitor the medication's effects on the liver.

      

    Alcohol

      

    There are no known interactions between Endobloc 5mg tablet and alcohol. However, excessive alcohol consumption can have negative effects on PAH and overall health. It's advisable to discuss alcohol consumption with your healthcare provider and consider moderation.

      

    Driving

      

    PAH can cause symptoms like dizziness and fatigue, which could impact driving safety. If you experience any side effects that affect your ability to drive, it's best to avoid driving until you feel safe to do so.

    Side Effects of Endobloc 5mg TabletEndobloc 5mg tablet causes some side effects like all medications, although not everyone will experience them. 

    Serious:

    • Liver problems
    • Anemia (low red blood cell count)
    • Fluid retention leading to heart failure exacerbation in certain individuals
    • Potential birth defects if taken during pregnancy

    Common:

    • Headache
    • Nasal congestion
    • Flushing
    • Peripheral edema (swelling in arms, legs, hands, or feet)

    Word of AdviceRegular liver function tests are important due to the possibility of liver problems. The medication is contraindicated during pregnancy due to potential birth defects. Careful monitoring for fluid retention is crucial, particularly in those with a history of heart failure. Anemia and decreased white blood cell counts can warrant regular blood tests. Informing healthcare providers of all medications being taken is essential to prevent potential interactions. Lung conditions should be communicated, as the medication's benefits and risks need to be carefully assessed. Lifestyle factors like alcohol consumption and smoking should be discussed, and any vision changes should be promptly reported. Individuals must be aware of the potential for allergic reactions. 

    FAQs Q 1. Is Endobloc 5mg tablet a cure for pulmonary arterial hypertension (PAH)?

    No, Endobloc 5mg tablet is not a cure for PAH. It is a medication that helps manage the symptoms and slow down the progression of the disease, improving quality of life and exercise capacity.

    Q 2. How long does it take for Endobloc 5mg tablet to start working?

    The effects of Endobloc 5mg tablet can vary from person to person. Some individuals may start experiencing improvements in exercise capacity and symptoms within a few weeks, while for others, it might take longer. Consistency in taking the medication as prescribed is important for optimal results.

    Q 3. Can Endobloc 5mg tablet be taken with other PAH medications?

    Yes, Endobloc 5mg tablet can be used alone or in combination with other PAH medications, depending on your specific condition and treatment plan. Your healthcare provider will determine the best approach for your situation.

    Q 4. What should I do if I miss a dose of Endobloc 5mg tablet?

    If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

    Q 5. Can Endobloc 5mg tablet be used in children with PAH?

    The safety and efficacy of Endobloc 5mg tablet in pediatric patients have not been well established, and its use in children and adolescents is limited. Its use should be carefully considered under the guidance of a healthcare professional.

    Q 6. Does Endobloc 5mg tablet cause weight gain?

    Weight gain, particularly due to fluid retention, is a potential side effect of Endobloc 5mg tablet. However, not everyone experiences this side effect. Regular monitoring by your healthcare provider can help manage any weight-related concerns.

    Fact Box of Endobloc 5mg Tablet

    Molecule name: Ambrisentan

    Therapeutic class: Antihypertensive Agents

    Pharmacological class: Endothelin receptor antagonist

    Indications: Pulmonary arterial hypertension

    Основные характеристики
    Manufacturer
    CIPLA LTD
    Origin of Medicine
    India
    Price for
    10 Tablet(s) In A Strip
    Salt Composition
    Ambrisentan
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