Active ingredient: Denosumab
Uses:
- Osteoporosis;
- Bone loss due to hormonal therapy in breast or prostate cancer;
- Multiple myeloma (cancer affecting plasma cells in the bone marrow);
- Bone metastases (cancer that spreads to bone).
Therapeutic effects:
- Reducing fracture risk;
- Increasing bone mineral density;
- Improving overall bone health.
Administration:
- Denosurel 120mg Injection is given as an injection by healthcare professionals.
- The dosage and duration of treatment are determined by a healthcare provider based on the individual's condition and response to the medication.
Storage:
- Store in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F).
- Do not freeze.
- Keep in the original package.
- Protect from light, moisture, and heat.
- Keep away from children and pets.
Safety advice:
- Pregnancy: the safety of using Denosurel 120mg Injection during pregnancy has not been established. Consult a doctor before considering its use.
- Breastfeeding: whether Denosurel 120mg Injection is excreted in milk is unknown. Consult a healthcare provider before taking this medication.
- Lungs: consult your healthcare provider if you have a lung or respiratory disorder history.
- Liver: Denosurel 120mg Injection is primarily metabolized in the liver, and its safety has not been extensively studied in individuals with severe liver impairment.
- Alcohol: it is generally recommended to avoid or limit alcohol consumption while taking Denosurel 120mg Injection.
- Driving: patients receiving Denosurel 120mg Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision.
Side effects:
- Serious: osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia.
- Common: injection site reactions, back pain, musculoskeletal pain, infections, abdominal pain, headache, hypophosphatemia.
FAQ:
Can Denosurel 120mg Injection be used in patients with a history of cancer? Denosurel 120mg Injection is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. Discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication.
Can Denosurel 120mg Injection be used in patients with kidney problems? Denosurel 120mg Injection is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function.
Can Denosurel 120mg Injection be used as a treatment for osteoporosis in men? Yes, Denosurel 120mg Injection is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis.
Can Denosurel 120mg Injection be used in children and adolescents with osteoporosis? Denosurel 120mg Injection is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.
Can Denosurel 120mg Injection be used in individuals with dental implants? Denosurel 120mg Injection use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Discuss this with your dentist and healthcare provider to assess Denosurel 120mg Injection's potential risks and benefits.
What are the side effects of Denosurel 120mg Injection? Denosurel 120mg Injection can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.
Fact box:
- Molecule name: Denosumab.
- Therapeutic class: Anti-resorptive agent.
- Pharmacological class: Monoclonal Antibodies.