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Характеристики:
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Manufacturer
CIPLA LTD
Origin of Medicine
India
Price for
1 Prefilled Syringe(s)
Salt Composition
Denosumab
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Denoci OP 60mg Injection
Description:
- Contains the active ingredient Denosumab.
- Used to treat osteoporosis, a condition characterized by weakened bones.
- Prescribed to prevent bone complications in patients with certain types of cancer, such as multiple myeloma and bone metastases.
Mechanism of Action:
- Inhibits a protein called RANK ligand, which plays a role in the breakdown of bone tissue.
- Significantly increases bone density, reducing fracture risk in postmenopausal women with osteoporosis and patients with cancer-related bone loss.
Uses:
- Osteoporosis.
- Bone loss due to hormonal therapy in breast or prostate cancer.
- Multiple myeloma (cancer affecting plasma cells in the bone marrow).
- Bone metastases (cancer that spreads to bone).
Therapeutic Effects:
- Reduces fracture risk.
- Increases bone mineral density.
- Improves overall bone health.
Interaction with Other Drugs:
- Inform the doctor about all the medicines, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products.
- Certain medications may interact with Denoci OP 60mg Injection and reduce effectiveness by causing undesirable side effects.
Storage:
- Store in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F).
- Do not freeze it.
- Keep in the original package.
- Keep away from light, moisture, and heat.
- Keep away from children and pets.
- Avoid taking double doses for missed doses.
Administration:
- Given as an injection by healthcare professionals.
- Dosage and duration of treatment will be based on the individual's condition and response to the medication and should be determined by a healthcare provider.
Safety Advices:
- Pregnancy: the safety of using Denoci OP 60mg Injection during pregnancy has not been established.
- Breastfeeding: whether Denoci OP 60mg Injection is excreted in milk is unknown.
- Lungs: consult your healthcare provider before taking Denoci OP 60mg Injection if you have a lung or respiratory disorders history.
- Liver: Denoci OP 60mg Injection is primarily metabolized in the liver, and its safety has not been extensively studied in individuals with severe liver impairment.
- Alcohol: it is generally recommended to avoid or limit alcohol consumption while taking Denoci OP 60mg Injection.
- Driving: patients receiving Denoci OP 60mg Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision.
Side Effects:
- Serious: osteonecrosis of the jaw (severe necrosis or death of jaw cells), atypical femoral fractures, hypocalcemia (low blood calcium levels).
- Common: injection site reactions, back pain, musculoskeletal pain, infections, abdominal pain, headache, hypophosphatemia (low blood phosphate levels).
Word of Advice:
- Attend all scheduled appointments and follow-up visits to monitor your response to treatment and address any concerns or side effects.
- Tell your doctor about your medical history, previous infection, liver disease, and kidney disease.
- Inform your healthcare provider about any allergies or hypersensitivity reactions you may have.
- Seek immediate medical attention if you experience severe allergic reactions or other serious side effects.
- Pregnant and breastfeeding women should consult a doctor before taking this medication.
- Avoid taking any vaccines during treatment.
- Regular dental examinations and good oral hygiene practices are recommended to minimize the risk of jaw osteonecrosis.
FAQs:
Q1. Can Denoci OP 60mg Injection be used in patients with a history of cancer?
- Denoci OP 60mg Injection is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. It is important to discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication.
Q2. Can Denoci OP 60mg Injection be used in patients with kidney problems?
- Denoci OP 60mg Injection is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function.
Q3. Can Denoci OP 60mg Injection be used as a treatment for osteoporosis in men?
- Yes, Denoci OP 60mg Injection is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis.
Q4. Can Denoci OP 60mg Injection be used in children and adolescents with osteoporosis?
- Denoci OP 60mg Injection is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.
Q5. Can Denoci OP 60mg Injection be used in individuals with dental implants?
- Denoci OP 60mg Injection use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Suppose you have dental implants or are considering getting them. In that case, it is important to discuss this with your dentist and healthcare provider to assess Denoci OP 60mg Injection's potential risks and benefits.
Q6. What are the side effects of Denoci OP 60mg injection?
- Denoci OP 60mg Injection can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.
Fact Box:
- Molecule name: Denosumab.
- Therapeutic class: Anti-resorptive agent.
- Pharmacological class: Monoclonal Antibodies.
- Indications:
- Osteoporosis.
- Bone loss due to hormonal therapy in breast or prostate cancer.
- Multiple myeloma.
- Bone metastases.
Основные характеристики
Manufacturer
CIPLA LTD
Origin of Medicine
India
Price for
1 Prefilled Syringe(s)
Salt Composition
Denosumab
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