Uses:
- Advanced renal cell carcinoma;
- Liver cancer (when Sorafenib is no longer working);
- Differentiated thyroid cancer.
Mechanism of action: Cabdual 60mg acts against a protein called receptor tyrosine kinases and interferes with cell signaling, ultimately stopping the growth and spread of cancer cells.
Dosage and administration:
- Take as advised by your physician, usually once a day;
- Do not crush, chew, or open the medicine;
- The correct dosage and duration are determined by the physician based on age, body weight, and disease condition.
Contraindications:
- Do not consume if you are allergic to Cabozantinib and its other ingredients;
- Not recommended for those younger than 18 years.
Warnings and precautions:
- Inform your physician if you have liver disease, inflammatory bowel disease, high blood pressure, heart disease, or diarrhea;
- Notify your doctor about the history of blood clots in the leg or significant bleeding, aneurysm, or tears in the blood vessel wall;
- Discuss fertility concerns with your doctor;
- Thyroid functions must be monitored before starting the medicine;
- Avoid taking grapefruit or grapefruit juice during the treatment;
- Store protected from light at a temperature not exceeding 30°C;
- Keep out of sight and reach of pets and children.
Side effects:
- Serious: gastrointestinal perforation, severe or uncontrollable bleeding, shortness of breath, nonhealing wound, pain in the mouth, jaw/teeth, hand, feet, loss of consciousness, drowsy, swelling or sores in the mouth, blood vomiting, black stools, blood in urine, headache, coughing blood;
- Common: dehydration, difficulty swallowing, ringing in the ears, blood clots in the veins, fluctuation in the blood sugar levels, the lower level of albumin, electrolyte imbalance, increased levels of liver enzymes, elevated cholesterol levels in the blood, hair loss, changes in hair color, muscle spasm, skin thickening, dry skin, itching, protein in urine.
Interaction with other drugs: Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications such as antibiotics, St. John's Wort, Aliskiren, and other medicine may interact with Cabdual 60mg and can cause undesirable side effects.
Pregnancy and breastfeeding:
- Cabdual 60mg is unsafe to use during pregnancy as it may harm the unborn baby;
- Taking Cabdual 60mg while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the treatment.
Driving: While taking Cabdual 60mg, it is unsafe to drive or use machines because it may cause nausea, changes in vision, vomiting, etc.
FAQ:
- Can Cabdual 60mg cause a lower level of albumin? One of the common side effects of Cabdual 60mg is the lower level of albumin. If you experience any side, contact your physician immediately.
- Why is it recommended to use effective contraception during the treatment of Cabdual 60mg? To avoid unwanted pregnancy, it is advised to use effective contraception. Oral contraception may be ineffective, so it is better to discuss effective contraception with your doctor.
- Why is liver enzyme getting elevated during treatment with Cabdual 60mg? The reason for this elevation is not completely understood, but it is thought to be related to the drug's effects on certain enzymes involved in liver function. The elevation in liver enzymes is generally mild and temporary and typically resolves on its own or with dose adjustment of the Cabdual 60mg tablet.
- How can I manage diarrhea while taking Cabdual 60mg? If you experience diarrhea while taking Cabdual 60mg, it is important to stay hydrated by drinking plenty of fluids. Your doctor may also recommend over-the-counter or prescription medications to help manage your diarrhea. If your diarrhea is severe or persistent, you should contact your doctor.
- Is Cabdual 60mg a chemotherapy drug? Yes, Cabdual 60mg is a chemotherapy medication that belongs to the group of Tyrosine kinase inhibitors.