Bonitar 400mg Tablet: Effective Relief for Your Needs

• Bonitar 400mg Tablet contains the active ingredient bosutinib.
• It belongs to the group of medications called Tyrosine kinase inhibitors.
• It is indicated to treat adult patients with a type of leukemia known as Philadelphia chromosome-positive (Ph-positive) Chronic Myeloid Leukaemia (CML) who have been newly diagnosed or for whom earlier CML treatments have either failed or have not worked or are not suitable.

Uses of Bonitar 400mg Tablet

• Treatment of Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML).

Therapeutic Effects

• Bonitar 400mg Tablet works by inhibiting the activity of an enzyme called Bcr-Abl kinase that promotes the growth and spread of blood cancer (Ph+ CML).
• This helps to slow or stop the growth and spread of cancer cells.

Interaction with Other Drugs

• Inform your doctor about any medications you are taking or have taken before the treatment.

Safety Advice

• Pregnancy: Bonitar 400mg Tablet is unsafe to use during pregnancy as it could cause potential harm to a developing baby. Consult the doctor before taking this medicine, and it will be given to you if clearly needed. Use effective birth control during and for 30 days (one month) after the last dose.
• Breastfeeding: Avoid breastfeeding while taking Bonitar 400mg Tablet, as it is not known whether it passes into the breast milk and harms your baby. Consult the doctor before taking this medication.
• Lungs: Inform your doctor if you have any lung conditions before starting treatment with Bonitar 400mg Tablet.
• Liver: Tell your doctor if you have a history of liver problems, including hepatitis, before taking Bonitar 400mg Tablet. Your doctor will perform blood tests to evaluate your liver function.
• Alcohol: Drinking a small amount of alcohol does not affect the safety or usefulness of Bonitar 400mg Tablet. As a precautionary measure, limit or avoid alcohol with this medication.
• Driving: Taking Bonitar 400mg Tablet can cause dizziness, blurred vision, or unusual tiredness. Do not drive if you feel unwell.

Side Effects

• Serious: Blood disorders (bleeding, fever, bruising), stomach problems (stomach pain, vomiting, diarrhea, constipation, nausea), hepatitis B reactivation, severe skin reactions, liver problems (yellowing of white part of eyes and skin, tea-colored urine), heart problems (loss of consciousness, irregular heartbeat).
• Common: Low white blood cell count (leukopenia), headache, dizziness, cough, shortness of breath, joint pain, back pain, decreased appetite, respiratory tract infection, increase in blood pressure, ringing in the ears (tinnitus), itching, acne, dehydration, taste change, sensitivity to light, fluid on lungs.

FAQs

1. Is Bonitar 400mg Tablet a chemotherapy medication?

   • Yes, Bonitar 400mg Tablet is a chemotherapy medication that is indicated to treat Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML) in adults.

2. What class of medication is Bonitar 400mg Tablet?

   • Bonitar 400mg Tablet belongs to the class of medications called tyrosine kinase inhibitors.

3. Can you crush Bonitar 400mg Tablet?

   • No, Bonitar 400mg Tablet should not be crushed or broken. It must be swallowed whole with a glass of water. Do not handle or touch the broken tablets.

4. What is the best time to take Bonitar 400mg Tablet?

   • It is best to take Bonitar 400mg Tablet once a day without food. Take the tablet at the same time every day for better results.

5. What happens if I miss my dose of Bonitar 400mg Tablet?

   • Take the recommended dose if you miss a dose of Bonitar 400mg Tablet by less than 12 hours. If you miss the dose by more than 12 hours, skip the missing dose and start your next dose at the regular time.

6. What should be avoided in Bonitar 400mg Tablet?

   • Grapefruit, its juices, and supplements that contain grapefruit extract should be avoided during treatment with Bonitar 400mg Tablet as it raises the blood level in your body.

7. Can children use Bonitar 400mg Tablet?

   • No, Bonitar 400mg Tablet is not recommended for usage in children under 18.

8. Who is contraindicated to take Bonitar 400mg Tablet?

   • Patients who have experienced allergic reactions (hypersensitivity) to Bonitar 400mg Tablet or have heart or bleeding problems, kidney or liver disorders, and pregnant and breastfeeding women should not use Bonitar 400mg Tablet.

Fact Box

• Molecule name: Bosutinib
• Therapeutic class: Tyrosine kinase inhibitors
• Pharmacological class: Antineoplastics
• Indications: Treatment of Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML).

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