Persistent, recurrent, or metastatic breast cancer;
Metastatic cervical cancer;
Advanced kidney cancer;
Metastatic colorectal cancer;
Advanced non-small-cell lung cancer;
Liver cancer — hepatocellular carcinoma;
Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer.
Therapeutic Effects:
Bevicra 100mg Injection is a recombinant humanized monoclonal antibody that works as a targeted therapy in the treatment of various advanced cancers.
It selectively binds to the protein called vascular endothelial growth factor A (VEGF-A), interrupting its interaction with receptors and inhibiting the formation of blood vessels that supply oxygen and nutrients to the tumor.
This slows down the rate of progression of cancer.
Administration:
Bevicra 100mg Injection is administered intravenously through infusion.
The amount of drug is measured based on the patient’s body weight, height, and age.
The first dose is administered for 90 minutes, and if well tolerated, the infusion time can be reduced to 30 minutes.
Safety Advice:
Pregnancy: Inform your physician before starting treatment with Bevicra 100mg Injection if you are pregnant or planning for pregnancy.
Breastfeeding: Avoid breastfeeding for a minimum of 6 months after treatment with Bevicra 100mg Injection.
Lungs: Inform your doctor if you have any lung conditions before starting treatment.
Liver: Inform your physician before starting Bevicra 100mg Injection if you have liver diseases.
Alcohol: Consult your doctor to know if it is safe to consume alcohol while on treatment with Bevicra 100mg Injection.
Driving: Avoid driving or using machinery while on treatment with Bevicra 100mg Injection, as it may cause dizziness or sleepiness.
Interaction with Other Drugs:
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment.
Certain medications may interact with Bevicra 100mg Injection and cause undesirable side effects.
Storage:
Store Bevicra 100mg Injection at 2˚C to 8˚C.
Do not freeze or shake.
Protect from light.
Keep out of reach of children.
Side Effects:
Serious: headache, vision changes, confusion, severe allergic reactions, high blood pressure, delayed wound healing following surgery, protein in urine, severe infections, blood clots in arteries and blood vessels of lungs, gut perforation, nosebleeds and bleeding risk, heart problems with an increase in heart rate, mouth sores, dryness, shortness of breath.
Common: numbness in hands or feet, weakness and lack of energy, diarrhea, nausea, vomiting, abdominal pain, constipation, loss of appetite, weight loss, changes in taste and speech, decrease in counts of white blood cells, fever, dry skin, back pain.
FAQs:
Is Bevicra 100mg Injection used as standalone treatment in cancers?
Bevicra 100mg Injection can be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.
Is it safe for women to use Bevicra 100mg Injection?
While for women with reproductive potential, it is advised to discuss with your doctor regarding effective birth control methods during the treatment.
Is it safe to undergo surgery during the treatment with Bevicra 100mg Injection?
Bevicra 100mg Injection is associated with an increased risk of bleeding complications and poor wound healing. Hence, it is suggested to avoid planning for surgery and maintain an interval of 28 days before or after surgery.
Do the side effects of Bevicra 100mg Injection last for a chronic period?
All the side effects that are relatively caused by Bevicra 100mg Injection occur until the drug concentration stays in the body. It is found that this medicine will be contained in the body for almost 4 months after the final dose.
How is Bevicra 100mg Injection administered?
Bevicra 100mg Injection is given intravenously through infusion, and the amount of drug will be measured based on the patient’s body weight, height, and age. The first dose will be administered for 90 minutes, and if well tolerated, the infusion time can be reduced to 30 minutes.
Can I take Bevicra 100mg Injection if I am pregnant?
Inform your physician before starting your treatment with Bevicra 100mg Injection if you are pregnant or planning for pregnancy, as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.
