Bevarest 400mg Injection is an anticancer medicine consisting of the active ingredient Bevacizumab.
It is developed to prevent the growth of tumors.
It is indicated along with other chemotherapy drugs to treat metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer.
It is also used to treat cancers of the ovary, fallopian tube, or primary peritoneal cancer.
Uses:
Glioblastoma multiforme (brain cancer)
Persistent, recurrent, or metastatic breast cancer
Metastatic cervical cancer
Advanced kidney cancer
Metastatic colorectal cancer
Advanced non-small-cell lung cancer
Liver cancer (Hepatocellular carcinoma)
Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer
Therapeutic Effects:
Bevarest 400mg Injection is a recombinant humanized monoclonal antibody that works as a targeted therapy in the treatment of various advanced cancers.
It selectively binds to the protein called vascular endothelial growth factor A (VEGF-A), interrupting its interaction with receptors and inhibiting the formation of blood vessels that supply oxygen and nutrients to the tumor.
Administration:
Bevarest 400mg Injection is administered intravenously through infusion.
The infusion should be given immediately after the dilution.
Safety Advices:
Pregnancy: Inform your physician before starting treatment with Bevarest 400mg Injection if you are pregnant or planning for pregnancy.
Breast Feeding: Avoid breastfeeding for a minimum of 6 months after treatment with Bevarest 400mg Injection.
Lungs: Inform your doctor if you have any lung conditions before starting treatment.
Liver: Inform your physician before starting Bevarest 400mg Injection if you have liver diseases.
Alcohol: Consult your doctor to know if it is safe to consume alcohol while on treatment.
Driving: Avoid driving or using machinery while on treatment.
Side Effects:
Serious: Headache, vision changes, confusion, severe allergic reactions, high blood pressure, delayed wound healing following surgery, protein in urine, severe infections, blood clots in arteries and blood vessels of lungs, gut perforation, nosebleeds and bleeding risk, heart problems with an increase in heart rate, mouth sores, dryness, shortness of breath.
Common: Numbness in hands or feet, weakness and lack of energy, diarrhea, nausea, vomiting, abdominal pain, constipation, loss of appetite, weight loss, changes in taste and speech, decrease in counts of white blood cells, fever, dry skin, back pain.
FAQs:
Q 1. Is Bevarest 400mg Injection used as standalone treatment in cancers?
Bevarest 400mg Injection can be used as monotherapy or in combination with chemotherapy or immunotherapy medications.
Q 2. Is it safe for women to use Bevarest 400mg Injection?
Women with reproductive potential should discuss effective birth control methods with their doctor during and after treatment.
Q 3. Is it safe to undergo a surgery during the treatment with Bevarest 400mg Injection?
Bevarest 400mg Injection is associated with increased risk of bleeding complications and poor wound healing. Avoid surgery within 28 days before or after treatment.
Q 4. Do the side effects of Bevarest 400mg Injection last for a chronic period?
Side effects occur until the drug concentration stays in the body, which is about 4 months after the final dose.
Q 5. How is Bevarest 400mg Injection administered?
Bevarest 400mg Injection is given intravenously through infusion, with the amount based on the patient’s body weight, height, and age. The first dose is administered for 90 minutes, and if well tolerated, the infusion time can be reduced to 30 minutes.
Q 6. Can I take Bevarest 400mg Injection if I am pregnant?
Inform your physician before starting treatment with Bevarest 400mg Injection if you are pregnant or planning for pregnancy.