Treatment of Acute Myeloid Leukemia with 20–30% blasts in patients who are not eligible for Haemopoietic stem cell transplant.
Intermediate-2 and High-risk Myelodysplastic syndrome (MDS).
Therapeutic Effects:
The active form of Azatend 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.
Interaction with other drugs:
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Azatend 100 mg injection and cause undesirable side effects.
Storage:
Store at room temperature (15–30°C).
If the product is reconstituted, it must be used immediately; if not, store at 2–8°C for not more than 8 hours.
Keep the injection out of sight and reach of children.
How to consume:
Take Azatend 100mg Injection only under the supervision of your physician.
Your physician will decide the dose based on your height, weight, and general condition.
Azatend 100mg Injection shall be given under the skin of your thigh, stomach, or upper arm.
Safety Advices:
Pregnancy: Azatend 100mg Injection could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.
Breast Feeding: Breastfeeding is not intended for patients on Azatend 100mg Injection therapy. Consult your physician for advice.
Lungs: It is not known whether it is safe to administer Azatend 100mg Injection in lung failure patients. Please consult your doctor.
Liver: Inform your physician if you have been told that you have a tumor in the liver cells.
Alcohol: It is not known whether it is safe to consume alcohol with Azatend 100mg Injection. Please consult your doctor.
Driving: It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking Azatend 100 mg injection.
Side Effects:
Serious: unexpected bleeding, with blood in stool and urine; fever; pneumonia, characterized by chest pain or breathlessness; allergic reaction with symptoms of swelling of lips, itching, or rashes; seizures, loss of consciousness, severe headache, or bleeding in the brain; frequent urination with pain or burning sensation.
Common: disturbances in the blood count (RBC, WBC, Platelets); nausea, vomiting, diarrhea; constipation; tiredness; skin reactions like redness and pain at the site of injection; decreased appetite; dizziness; pain in extremities; joint pain; stomach pain; headache; sore nose and throat; rashes and bruising.
Word of Advice:
Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition.
Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects in the developing baby.
FAQs:
Q 1. How to use Azatend 100mg Injection?
Take only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. Azatend 100mg Injection is administered under the skin of your thigh, stomach, or upper arm.
Q 2. Does Azatend 100mg Injection cause hair loss?
No, Azatend 100mg Injection does not cause hair loss even after using it for a prolonged period of time.
Q 3. How does Azatend 100mg Injection work?
Azatend 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.
Q 4. Is Azatend 100mg Injection chemotherapy?
Yes. Azatend 100mg Injection is chemotherapy and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases the growth and multiplication (cytotoxic effect).
Q 5. What are the side effects of Azatend 100mg Injection?
The common side effects of Azatend 100mg Injection are nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat, and nose.
Q 6. Is it safe to drive after taking an Azatend 100mg Injection?
It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.
Fact Box:
Molecule name: Azacitidine.
Therapeutic class: Anti-metabolites.
Pharmacological class: Anti-Neoplastics.
Indications:
Treat advanced or metastatic non-small lung cancer (NSCLC).
