Avangio 400mg Injection: Effective Medication for Your Treatment

Avangio 400mg Injection

Uses

• Glioblastoma multiforme (brain cancer)
• Persistent, recurrent, or metastatic breast cancer
• Metastatic cervical cancer
• Advanced kidney cancer
• Metastatic colorectal cancer
• Advanced non-small-cell lung cancer
• Liver cancer — hepatocellular carcinoma
• Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer

Therapeutic Effects

• Avangio 400mg Injection is a recombinant humanized monoclonal antibody that works as a targeted therapy in the treatment of various advanced cancers.
• It selectively binds to the protein called vascular endothelial growth factor A (VEGF-A), interrupting its interaction with receptors and inhibiting the formation of blood vessels that supply oxygen and nutrients to the tumor.
• This slows down the rate of progression of cancer.

Interaction with Other Drugs

• Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment.
• Certain medications may interact with Avangio 400mg Injection and cause undesirable side effects.

Storage

• Store Avangio 400mg Injection at 2˚C to 8˚C. Do not freeze or shake.
• Protect from light.
• Keep out of reach of children.

Administration

• Your physician or nurse will administer Avangio 400mg Injection as an intravenous infusion.
• The infusion should be given immediately after the dilution.

Safety Advice

• Pregnancy: Inform your physician before starting treatment with Avangio 400mg Injection if you are pregnant or planning for pregnancy.
• Breastfeeding: Avoid breastfeeding for a minimum of 6 months after your treatment with Avangio 400mg Injection.
• Lungs: Inform your doctor if you have any lung conditions before starting treatment.
• Liver: Inform your physician before starting Avangio 400mg Injection if you have liver diseases.
• Alcohol: Consult your doctor to know if it is safe to consume alcohol while you are on treatment.
• Driving: Avoid driving or using machinery while you are on treatment as it may cause dizziness or sleepiness.

Side Effects

• Serious: headache, vision changes, confusion, severe allergic reactions, high blood pressure, delayed wound healing following surgery, protein in urine, severe infections, blood clots in arteries and blood vessels of lungs, gut perforation, nosebleeds and bleeding risk, heart problems with an increase in heart rate, mouth sores, dryness, shortness of breath.
• Common: numbness in hands or feet, weakness and lack of energy, diarrhoea, nausea, vomiting, abdominal pain, constipation, loss of appetite, weight loss, changes in taste and speech, decrease in counts of white blood cells, fever, dry skin, back pain.

FAQs

1. Is Avangio 400mg Injection used as standalone treatment in cancers?
   • Avangio 400mg Injection can be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.
2. Is it safe for women to use Avangio 400mg Injection?
   • Women with reproductive potential should discuss effective birth control methods during treatment and for at least 6 months after the course completion.
3. Is it safe to undergo surgery during the treatment with Avangio 400mg Injection?
   • Avoid surgery during treatment due to the risk of bleeding complications and poor wound healing. Maintain an interval of 28 days before or after surgery.
4. Do the side effects of Avangio 400mg Injection last for a chronic period?
   • Side effects occur until the drug concentration stays in the body, which is about 4 months after the final dose.
5. How is Avangio 400mg Injection administered?
   • Avangio 400mg Injection is given intravenously through infusion. The amount of drug will be measured based on the patient’s body weight, height, and age. The first dose will be administered for 90 minutes, and if well tolerated, the infusion time can be reduced to 30 minutes.
6. Can I take Avangio 400mg Injection if I am pregnant?
   • Inform your physician before starting treatment if you are pregnant or planning for pregnancy.

Fact Box

• Molecule name: Bevacizumab
• Therapeutic class: Anticancer
• Pharmacological class: VEGF Inhibitor

Tags: medical-injection, avangio, pain-relief, pharmaceutical-drug, anti-inflammatory