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₹1 395 000

Koselugo 25mg Capsule

Product Code: MRM_202718
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₹1 395 000
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Manufacturer
ASTRAZENECA PHARMA INDIA LTD
Origin of Medicine
United Kingdom
Price for
60 Capsule(s) In A Bottle
Salt Composition
Selumetinib
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Koselugo 25mg Capsule contains an active component called Selumetinib. It is a medication used in the treatment of certain types of cancers, particularly melanoma (a type of skin cancer) and other solid tumors, including non-small cell lung cancer and ovarian cancer, especially in cases where there's a specific genetic mutation that makes the cancer cells sensitive to MEK inhibitors. It may be prescribed for patients with advanced melanoma that has a specific genetic mutation, often BRAF-mutant melanoma. It has shown promise in treating plexiform neurofibromas, tumors associated with NF1, a genetic disorder that causes tumors to grow on nerves. 

Individuals who have had a severe allergic reaction to Koselugo 25mg Capsule or any of its components should not take this medication. It may cause harm to an unborn baby, so it is not recommended for use during pregnancy.  Patients with pre-existing heart conditions or a history of heart problems may need close monitoring or might not be suitable candidates for this medication. Older individuals, especially those over 65, may have an increased risk of certain side effects. Close monitoring for adverse reactions is typically recommended after taking this medication. The safety and efficacy of Koselugo 25mg Capsule in children under specific ages may not be well-established. 

Uses of Koselugo 25mg CapsuleUses of Koselugo 25mg Capsule

  • Melanoma treatment
  • Neurofibromatosis type 1 (NF1)
  • Solid tumor treatment

Therapeutic Effects of Koselugo 25mg Capsule

Koselugo 25mg Capsule is a medication that targets a specific cellular pathway called the MEK pathway, which is crucial for regulating cell growth. In cancers like melanoma and certain tumors, it blocks this pathway, disrupting signals that promote uncontrolled cell growth. By inhibiting this pathway, it slows down or halts the progression of cancer cells, reducing tumor growth and spread.

Interaction of Koselugo 25mg Capsule with other drugsInform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Koselugo 25mg Capsule, reducing effectiveness by causing undesirable side effects. 

More Information about Koselugo 25mg Capsule More information:

  • Stored at controlled room temperature, between 20°C to 25°C
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Koselugo 25mg CapsuleKoselugo 25mg Capsule is primarily administered orally, typically as capsules. The healthcare provider will determine the dosage and duration of treatment based on the specific infection and individual factors.

Safety Advices for Koselugo 25mg Capsule

  

Pregnancy

  

It is not safe to take Koselugo 25mg Capsule during pregnancy as it may cause harm to the unborn baby.

  

Breast Feeding

  

It is not safe to breastfeed while taking Koselugo 25mg Capsule, as it may pass into breast milk and harm the infant.

  

Lungs

  

Consult your health care provider before taking Koselugo 25mg Capsule if you have lung disease.

  

Liver

  

If you have a liver condition or are concerned about the safety of Koselugo 25mg Capsule, it is recommended to consult your healthcare provider for personalized advice.

  

Alcohol

  

There are no specific interactions between alcohol and Koselugo 25mg Capsule, but alcohol consumption might exacerbate certain side effects, such as dizziness or liver-related problems. It is advisable to consult a healthcare professional regarding alcohol consumption while on this medication.

  

Driving

  

Taking Koselugo 25mg Capsule while driving is unsafe as it might cause dizziness or visual disturbances as side effects, which could affect the ability to drive or operate machinery.

Side Effects of Koselugo 25mg CapsuleKoselugo 25mg Capsule causes some side effects like all medications, although not everyone will experience them. 

Serious:

  • Heart problems
  • Eye problems
  • Interstitial lung disease (ILD)
  • Liver problems
  • Skin toxicities

Common:

  • Nausea and vomiting
  • Diarrhea
  • Fatigue
  • Skin rash
  • Swelling or fluid retention

Word of AdviceRegular monitoring of heart function, including ECGs and cardiac assessments, may be necessary due to potential heart-related side effects while using Koselugo 25mg Capsule. Periodic eye exams are recommended as this medication might cause vision changes or retinal vein occlusion. Patients require monitoring for signs of interstitial lung disease (ILD) or breathing difficulties. Monitoring liver function through blood tests is essential due to the potential for elevated liver enzymes or liver damage.  Live vaccines should generally be avoided during treatment due to potential complications.  Regular monitoring might be necessary for individuals with existing endocrine conditions. Discuss with a healthcare professional regarding other medications, including over-the-counter drugs, herbal supplements, or vitamins, to avoid potential interactions with this medication.

FAQs Q 1. What are the common side effects of Koselugo 25mg Capsule?

Common side effects of Koselugo 25mg Capsule may include nausea, vomiting, diarrhea, fatigue, skin rash, and swelling.

Q 2. Are there any dietary restrictions while taking Koselugo 25mg Capsule?

No specific dietary restrictions are known while taking Koselugo 25mg Capsule, but following a balanced diet is advisable unless otherwise instructed by a healthcare professional.

Q 3. What should I do if I miss a dose of Koselugo 25mg Capsule?

If you miss a dose of Koselugo 25mg Capsule, take it as soon as you remember unless it's close to the next scheduled dose. Do not double the dose to catch up. Contact your healthcare provider for guidance.

Q 4. How long does it take for Koselugo 25mg Capsule to work?

The response to Koselugo 25mg Capsule can vary among individuals. Some may experience a reduction in tumor size or symptoms within weeks to months, while others may take longer to see noticeable effects.

Q 5. Can Koselugo 25mg Capsule cure cancer?

Koselugo 25mg Capsule is a treatment that aims to control the growth and spread of cancer cells. It may shrink tumors and improve symptoms, but its ability to completely cure cancer varies based on individual circumstances and the type and stage of cancer.

Q 6. How often must I undergo medical tests while taking Koselugo 25mg Capsule?

The frequency of medical tests for Koselugo 25mg Capsule, such as blood tests or imaging studies, will depend on individual factors and your healthcare provider's recommendations. Monitoring is often necessary to manage potential side effects and track treatment progress.

Fact Box of Koselugo 25mg Capsule

Molecule name:  Selumetinib

Therapeutic class: Antineoplastic agents

Pharmacological class: Mitogen-activated protein Kinase (MAPK) inhibitor

Indications: 

1. Melanoma treatment

2. Neurofibromatosis type 1 (NF1) 

3. Solid tumor treatment 

Основные характеристики
Manufacturer
ASTRAZENECA PHARMA INDIA LTD
Origin of Medicine
United Kingdom
Price for
60 Capsule(s) In A Bottle
Salt Composition
Selumetinib
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