Apotinib 400mg Tablet
Uses:
- Chronic myeloid leukemia (CML);
- Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL);
- Myelodysplastic/myeloproliferative diseases (MDS/MPD);
- Hypereosinophilic syndrome (HES);
- Chronic eosinophilic leukemia (CEL);
- Dermatofibrosarcoma protuberans (DFSP);
- Gastrointestinal stromal tumors (GIST).
Therapeutic Effects:
- Apotinib 400mg tablet is a protein-tyrosine kinase inhibitor that blocks a specific abnormal protein created by a chromosomal abnormality that signals cancer cells to multiply.
- It inhibits the multiplication and induces cell death in abnormal cancer cells.
Interaction with other drugs:
- Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products.
- Certain medications may interact with the effects of Apotinib 400mg tablet and reduce its effectiveness by causing undesirable side effects.
Safety Advices:
- Pregnancy: Apotinib 400mg tablet is unsafe to administer in pregnant women because it may affect the fetus.
- Breastfeeding: Breastfeeding is not recommended in patients taking Apotinib 400mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby.
- Lungs: It is unknown whether Apotinib 400mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
- Liver: Apotinib 400mg tablet is unsafe when administered in patients with severe liver diseases. Dose adjustments are necessary in severe liver failure.
- Alcohol: It is unknown whether it is safe to consume alcohol when taking Apotinib 400mg tablet. Consult your doctor for more advice.
- Driving: It is unsafe to drive or operate heavy machinery after taking Apotinib 400mg tablet because you may feel dizzy, drowsy, or get blurred vision.
How to consume:
- Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors.
- Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water.
- Take this medicine with a meal to avoid stomach problems.
- If you are unable to swallow the tablets, you can dissolve them as per your doctor's advice.
Side Effects:
- Common: swelling in the face, legs, ankles, and feet; nausea, vomiting; muscle cramps and pain; diarrhea; skin rash, night sweats; tiredness, dizziness; abdominal pain; increased weight; decreased RBC and WBC cells; headache; cough, inflammation in the nose; fever, lack of sleep.
- Serious: heart failure; GI disorders; hypothyroidism; liver failure; swelling in the body.
Word of Advice:
- You may become more sensitive to the sun while taking Apotinib 400mg tablets. It is important to cover sun-exposed areas of skin and use sunscreen with a high sun protection factor after consulting with your doctor.
- The medicine should be administered cautiously in patients with kidney problems.
- This tablet may cause your body to retain water, inform your physician if you put on weight very quickly after the therapy.
- Your doctor will regularly do lab tests to check whether the medicine works.
FAQs:
How to use Apotinib 400mg tablet? Apotinib 400mg tablet is administered orally, in the form of a tablet or capsule, and the dose depends on several factors, including the condition being treated, the weight of the patient, the particular regimen being used, and the overall health of the patient. It should be taken with food and a large glass of water to minimize gastrointestinal irritation.
Ever since I started using Apotinib 400mg tablet, I have noticed rashes and severe itching when I have sun exposure. Is it because of the medicine or the disease? This medicine may make your skin much more sensitive to sunlight than it normally is. Exposure to sunlight may cause skin rash, itching, redness, or severe sunburn. When you are outdoors, wear protective clothing and use sunscreen with an SPF. Consult your doctor before taking necessary precautions.
Can Apotinib 400mg tablet cause kidney damage? Yes, when taken for a longer period the medicine may cause damage to your kidneys. Your doctors may recommend you take a routine blood tests to assess your kidney function.
When is the best time to take Apotinib 400mg tablet? Take the tablet as prescribed by your doctor. Take Apotinib 400mg tablet at the same time every day. It is usually taken with a meal and a large glass of water to avoid stomach problems.
Does Apotinib 400mg tablet affect memory? Memory impairments have been only reported in limited studies. Consult your doctor immediately if you have any trouble in concentrating.
Fact Box:
- Molecule name: Imatinib;
- Therapeutic class: Antineoplastics;
- Pharmacological class: Tyrosine kinase inhibitor;
- Indications: Treat certain type of leukemia and other cancers and disorders of the blood cells.