Active ingredient: Lenvatinib
Therapeutic class: Anticancer
Pharmacological class: Tyrosine kinase inhibitor
Indications:
- Certain types of advanced thyroid cancer when radioactive iodine therapy is not beneficial.
- Advanced liver cancer in patients who are not eligible for surgical treatment.
- Certain types of kidney cancer.
- Endometrial cancer.
Mechanism of action:
Adlante 10mg Capsule blocks the enzyme receptor tyrosine kinases (RTKs), which are present in high concentrations in cancer cells. RTKs develop new blood vessels that supply oxygen and nutrients to the cells and help them grow. By inhibiting these receptors, the medicine slows down the rate of cancer cells’ growth and multiplication.
Important information:
- Patients who have had an allergic reaction to Adlante 10mg Capsule or any of its components should not take this medication.
- Patients should inform their dentist or oral surgeon that they are taking Adlante 10mg Capsule, as it can impair wound healing and increase the risk of bleeding.
- Adlante 10mg Capsule is unsafe during pregnancy as it can cause fetal harm. It is recommended to avoid this medication during pregnancy.
- Breastfeeding is not recommended while taking Adlante 10mg Capsule, as it can potentially harm the nursing infant.
- Adlante 10mg Capsule can cause side effects that affect the lungs, such as cough, shortness of breath, and difficulty breathing. If a person experiences any of these symptoms while taking it, they should notify their healthcare provider right away.
- Adlante 10mg Capsule is primarily metabolized in the liver, so inform your healthcare provider if you have any liver problems or diseases.
- It is recommended to avoid consuming alcohol while taking Adlante 10mg Capsule, as alcohol can increase the risk of certain side effects associated with the medication.
- Patients receiving Adlante 10mg Capsule should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision.
Dosage and administration:
Adlante 10mg Capsule is an oral medication that is usually taken once a day, at approximately the same time each day, with or without food. It should be taken as prescribed by a doctor or other healthcare provider. These capsules should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect the way the medication is absorbed and decrease its effectiveness.
Storage:
- Store at room temperature, between 20°C to 25°C (68°F to 77°F).
- Protect from light.
- Keep in its original packaging until it is ready to be used.
- Keep out of reach of children and pets.
- Dispose of properly.
Side effects:
Serious:
- Feeling numb or weak on one side of the body.
- Severe headache.
- Fever.
- Confusion.
- Difficulty speaking.
- Vision changes.
- Dizziness.
- Chest pain or pressure.
- Pain in arms, jaw, neck, and back.
- Breathing problems.
- Severe stomach pain.
- Blood clot formation.
- Blood in stools or coughing blood.
- Liver problems.
- Pain or soreness in the mouth, teeth, or jaw.
Common:
- High or low blood pressure.
- Loss of appetite.
- Nausea, vomiting, constipation, diarrhea, or indigestion.
- Tiredness.
- Hoarse voice.
- Leg swelling.
- Rashes.
- Pain in joints or muscles.
- Hair loss.
- Sleeplessness.
- Protein in urine, frequent urination.
- Low potassium, magnesium, and calcium levels in the blood.
- Dehydration.
- Skin problems.
- Gall bladder inflammation.
- Increase in the values of cholesterol, thyroid-stimulating hormone, digestive enzymes.
- Delayed wound healing.
FAQs:
Q 1. Can Adlante 10mg Capsule cause infertility?
Adlante 10mg Capsule can cause changes in menstrual periods and may affect fertility in some women. Patients should discuss their fertility concerns with their healthcare provider before starting this medication.
Q 2. Can Adlante 10mg Capsule cause hair loss?
Yes, hair loss is a potential side effect of Adlante 10mg Capsule. However, not all patients experience hair loss while taking this medication. Patients should discuss the potential side effects with their healthcare provider before starting treatment.
Q 3. Can Adlante 10mg Capsule cause heart problems?
Adlante 10mg Capsule can cause high blood pressure, which may increase the risk of heart problems. Patients should have their blood pressure monitored regularly while taking this medication.
Q 4. Can I go for teeth extraction if I am taking Adlante 10mg Capsule?
Before undergoing any dental procedures, it's important to inform your dentist and healthcare provider that you are taking Adlante 10mg Capsules. It can increase the risk of bleeding, and dental procedures that involve cutting or removing tissue may increase this risk further. Your healthcare provider and dentist may recommend taking certain precautions, such as temporarily stopping of this medication before the procedure or adjusting your medication dose.
Q 5. Can Adlante 10mg Capsule cause vision problems?
Yes, vision problems are a potential side effect of Adlante 10mg Capsule. Patients should report any changes in vision to their healthcare provider immediately.
Q 6. Can Adlante 10mg Capsule be used in children?
Adlante 10mg Capsule is not currently approved for use in children. The safety and efficacy in children have not been established.