Belongs to the class of medications called hematopoietic growth factors.
Used to treat anemia (lower than normal red blood cells) in people with chronic kidney disease.
Also indicated to treat anemia caused by chemotherapy in people with certain types of cancer.
Uses:
To treat anemia in chronic kidney failure.
To treat anemia caused by chemotherapy.
Mechanism of Action:
Erythropoiesis-stimulating protein produced by recombinant DNA technology.
Closely related to erythropoietin and stimulates erythropoiesis by the same mechanism.
Binds to progenitor stem cells stimulating the production/differentiation of red blood cells.
Works by causing the bone marrow to make more red blood cells.
Important Safety Information:
Allergies: Do not take if you are allergic to Darbepoetin alfa or any other ingredients and have uncontrolled blood pressure.
Medical Conditions: Inform your physician if you have high blood pressure, anemia, a history of seizures, epilepsy, liver disease, or allergy to latex or hepatitis C.
Pregnancy and Breastfeeding: Inform your physician if you are pregnant or breastfeeding.
Side Effects: If you have severe headache, dizziness, drowsiness, confusion, problems with your eyesight, nausea, vomiting, or seizures after taking Actorise 40mcg injection, inform your physician immediately and seek medical advice.
Storage:
Store in a refrigerator (2°C to 8°C).
Do not freeze.
Store in the original package to protect from light.
Keep the injection away from the reach of children and pets.
Administration:
This injection is to be given under the skin (subcutaneous).
Your doctor, nurse, or other healthcare professional will train you on how to inject yourself with this pre-filled pen.
Do not try to inject the pre-filled pen if you are not well-trained.
Never inject the medicine into your vein.
Safety Advices:
Pregnancy: There are no adequate and well-controlled studies on the use of Actorise 40mcg injection in pregnant women.
Breastfeeding: Breastfeeding is not recommended in patients taking Actorise 40mcg injection.
Lungs: It is unknown whether Actorise 40mcg injection can be used in patients with lung disorders.
Liver: Actorise 40mcg injection is unsafe to administer in patients with liver problems.
Alcohol: It is unknown whether consuming alcohol is safe during the treatment with Actorise 40mcg injection.
Driving: Actorise 40mcg injection will not make you feel tired, dizzy, or sleepy. It is safe to drive or operate heavy machinery after taking this medicine.
Side Effects:
Common: Swelling in the face and body, low blood pressure, abdominal pain, shortness of breath, cough.
Your doctor will prescribe your exact dose and tell you how often it should be given.
Make sure you understand all instructions before giving yourself an injection.
Do not use more medicine or use it more often than your doctor tells you to.
FAQs:
Can Actorise 40mcg injection be used in patients with kidney failure who are undergoing dialysis?
Yes, Actorise 40mcg injection is commonly used in patients with kidney failure who are undergoing dialysis to manage anemia.
Can Actorise 40mcg injection be used in patients with a history of heart disease?
Actorise 40mcg injection should be used with caution in patients with a history of heart disease, as it may increase the risk of certain cardiovascular events.
Can Actorise 40mcg injection be used to treat anemia caused by nutritional deficiencies?
Actorise 40mcg injection is not typically used to treat anemia caused by nutritional deficiencies.
Can Actorise 40mcg injection be used to treat anemia in patients undergoing radiation therapy?
Actorise 40mcg injection is used to treat anemia in patients undergoing chemotherapy, depending on the specific circumstances and the healthcare provider's recommendation.
Can Actorise 40mcg injection interact with other medications?
Actorise 40mcg injection may interact with certain medications, such as blood thinners or immunosuppressants.