Description
- Class: Antineoplastic drug, alkylating agent.
- Active ingredient: Bendamustine.
Uses
- Chronic lymphocytic leukaemia.
- Non-Hodgkin’s lymphomas.
- Multiple myeloma.
Mechanism of action
- Causes DNA damage and disrupts the cell cycle, leading to cancer cell death.
- Forms covalent bonds with DNA, inhibits DNA repair enzymes, and blocks cell cycle progression.
Administration
- Given intravenously into a vein in the arm or hand.
- Typically administered once every three to four weeks.
- Usually given about 30 minutes before chemotherapy or right before anaesthesia for surgery.
Important information
- Store in the refrigerator (2°-8°C), do not freeze.
- Keep out of reach from children and pets.
- Consult a doctor if you missed the scheduled dose.
Safety advice
- Pregnancy: not recommended as it may cause fetal harm.
- Breastfeeding: consult a doctor before breastfeeding.
- Lungs: consult a doctor if you have any lung diseases.
- Liver: inform your doctor if you have any liver problems.
- Alcohol: consuming alcohol may affect the effectiveness of the drug.
- Driving: it is unsafe to drive vehicles or operate heavy machinery after taking the drug, as it may cause dizziness and impair concentration.
Side effects
- Serious: severe allergic reactions, bone marrow suppression, abnormal liver function, tumor lysis syndrome.
- Common: infection, fever, low blood cell count, headache, dizziness, nausea, vomiting, increased blood level of creatinine and urea, mucosal inflammation, sore mouth, insomnia, fatigue, hair loss, itching, rash, diarrhea, constipation, missed periods, dehydration, loss of appetite, low or high blood pressure.
FAQs
What is Acodamust 100mg Injection used for? Acodamust 100mg Injection is a chemotherapy drug used to treat various types of cancers, including non-Hodgkin's lymphoma, chronic lymphocytic leukaemia, and multiple myeloma.
How will I receive Acodamust 100mg Injection? Acodamust 100mg Injection is administered into a vein as a short-term infusion over 30–60 minutes.
How does Acodamust 100mg Injection work to treat cancer? Acodamust 100mg Injection works by damaging the DNA in cancer cells, preventing them from multiplying and spreading.
Can Acodamust 100mg Injection be used in combination with other drugs? Yes, Acodamust 100mg Injection is often used in combination with other chemotherapy drugs to improve treatment outcomes.
Is Acodamust 100mg Injection safe to use during pregnancy? Acodamust 100mg Injection is not recommended during pregnancy as it may harm a developing fetus.
Who should not take Acodamust 100mg Injection? Acodamust 100mg Injection should not be taken by individuals who are allergic to it or its ingredients.
Fact box
- Molecule name: Bendamustine.
- Therapeutic class: Antineoplastics.
- Pharmacological class: Alkylating agents.