Belongs to the class of medications called anti-CD20 monoclonal antibodies.
Uses
Non-Hodgkin’s lymphoma (cancer affecting white blood cells called B-lymphocytes).
Chronic lymphocytic leukemia (a common form of cancer that affects B-cells).
Rheumatoid arthritis (a type of disease where the immune system attacks the body cells of its own joints) in combination with methotrexate.
Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels that mainly affects the lungs and kidneys).
Pemphigus vulgaris (an autoimmune condition that causes painful blisters on the skin and lining of the mouth, throat, nose, and genitals).
Important Information
Do not take if you are allergic to rituximab or any other ingredients of this medicine.
Do not take if you have a weak immune system or any severe active infection.
Inform your physician if you have heart disease, heart failure, or breathing problems before initiating the treatment.
Talk with your doctor if you have ever had a hepatitis B infection.
Pregnancy and breastfeeding are not recommended when you are taking this injection.
Side Effects
Common side effects include infection of the blood, reduced red blood cells, dizziness, swelling in the face and body, itchy skin, diarrhea, increased sweating, and low or high blood pressure.
Serious side effects include increased or decreased blood pressure, chest pain, hypersensitivity reactions, hepatitis B viral infection, memory loss, trouble thinking, difficulty in walking.
Therapeutic Effects
Veltiro 500mg injection is a monoclonal antibody that targets the antigen CD20 expressed on the cell surface of B-lymphocytes.
Induces cell death in NHL and CLL.
Blocks cell activation and growth and cause anticancer effects.
Inhibits rheumatoid factor production, antigen presentation, T-cell activation, and proinflammatory cytokine production in rheumatoid arthritis.
Interaction with Other Drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products.
Certain medications may interact with Veltiro 500mg injection and reduce its effectiveness by causing undesirable side effects.
Storage
Store Veltiro 500mg injection in the refrigerator (2°C to 8°C).
Do not freeze.
Keep the injection away from the reach of children and pets.
Administration
Should only be administered by a trained doctor or nurse.
Do not self-administer the injection.
Before giving Veltiro 500mg injection, you will be given other medications (pre-medication) to reduce the possible side effects.
Your doctor will decide the dose and duration of your treatment based on the disease severity and other factors.
It will be given as an intravenous infusion, and you will be monitored carefully for any unwanted side effects.
Safety Advice
Pregnancy: Veltiro 500mg injection is unsafe to administer in pregnant women because it may affect the fetus.
Breastfeeding: Breastfeeding is not recommended in patients taking Veltiro 500mg injection.
Lungs: It is unknown whether Veltiro 500mg injection can be used in patients with lung disorders.
Liver: Whether Veltiro 500mg injection can be used in patients with liver impairment is unknown.
Alcohol: Consuming alcohol may affect the effectiveness of Veltiro 500mg injection.
Driving: Caution is required while driving and operating machinery when you take Veltiro 500mg injection.
FAQs
Q1. What are the special precautions I should be aware of before starting treatment with Veltiro 500mg injection?
Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history.
Q2. Does Veltiro 500mg injection suppress the immune system?
Yes, it can suppress the immune system, and the chances of catching an infection are high.
Q3. What are Veltiro 500mg infusion-related reactions?
Infusion reactions occur during or within 24 hours after administering Veltiro 500mg injection. The symptoms are fever, chills, cough, itchy skin, nausea, vomiting, flushing, increased heart rate, and discomfort in the throat.
Q4. What will be the most important thing to monitor during Veltiro 500mg injection?
Your healthcare professional will monitor you carefully for unwanted side effects during the Veltiro 500mg injection.
Q5. Is weight gain a side effect of Veltiro 500mg injection?
Weight gain has been reported in patients treated with Veltiro 500mg injection for non-Hodgkin’s lymphoma.
-200x200.jpg "T-Jaki 11 XR Tablet")
