Belongs to the class of cancer medications known as PARP (poly [adenosine diphosphate-ribose] polymerase inhibitor) inhibitors.
Contains the active ingredient Olaparib.
Works by inhibiting the enzyme poly (ADP-ribose) polymerase (PARP), which plays a role in repairing damaged DNA in cells. By inhibiting PARP, Obrenza 100mg Tablet prevents cancer cells from repairing their DNA, leading to cell death.
Uses:
Maintenance therapy for various types of advanced ovarian cancer.
Treatment of early and metastatic breast cancer.
Treatment of prostate cancer.
Metastatic pancreatic cancer.
Dosage and Administration:
Available as a tablet to be taken with or without food, as directed by your healthcare provider.
The dose will be decided by your healthcare professional based on your conditions.
Avoid crushing, opening, or dissolving the tablet and swallow it whole with a glass of water.
Take the Obrenza 100mg Tablet at the same time every day.
Contraindications:
Not recommended to take Olaparib if you are allergic to the active compound and other ingredients of the medicine.
Consult your doctor immediately if you experience breathlessness, chest pain, rapid heart rate, fever, cough, or wheezing.
Not advised to use this medication while pregnant since it may harm the fetus and cause miscarriage.
Not recommended to breastfeed during and after 1 month of completion of therapy.
Inform your doctor about all the medicines you are taking, including prescription, over-the-counter drugs, vitamins, and supplements.
Safety Advice:
Pregnancy: it is not recommended to take Obrenza 100mg Tablet during pregnancy as it may harm your unborn baby.
Breastfeeding: it is unknown whether Obrenza 100mg Tablet passes into the breast milk.
Lungs: consult your doctor if you have any lung diseases before starting the treatment.
Liver: inform your physician if you have any liver problems before starting the treatment.
Alcohol: it is unknown whether consuming alcohol interacts with the Obrenza 100mg Tablet.
Driving: Obrenza 100mg Tablet may have an impact on your ability to operate machinery and drive.
Side Effects:
Common: shortness of breath, nausea, vomiting, fatigue, dyspepsia, loss of appetite, dizziness, diarrhea, headache.
Obrenza 100mg Tablet can lower blood cell counts, thus it's best to get blood tests done at regular intervals.
Stay out of direct sunlight and wear sunscreen with an SPF of at least 50 before going outside.
Obrenza 100mg Tablet should not be stopped without first talking to your doctor.
Stay away from grapefruit juice as it may raise your blood levels of the drug.
Maintain a sufficient fluid intake because dehydration can exacerbate symptoms such as diarrhea and other gastrointestinal disorders.
FAQs:
Can Obrenza 100mg Tablet be taken during pregnancy or breastfeeding?
Obrenza 100mg Tablet may harm an unborn baby and should not be used during pregnancy. It is also not recommended while breastfeeding, as it may pass into breast milk and harm the nursing infant.
What are Obrenza 100mg Tablet's typical side effects?
Nausea, vomiting, lethargy, diarrhea, appetite loss, and blood cell count abnormalities are typical adverse effects.
Are there any dietary restrictions I need to follow while on Obrenza 100mg Tablet?
There are no specific dietary restrictions associated with Obrenza 100mg Tablet. However, it's essential to maintain a healthy and balanced diet to support your overall well-being during treatment. It is recommended to avoid grape juice as it increases the blood drug concentration.
Is Obrenza 100mg Tablet used as a standalone treatment in cancers?
Obrenza 100mg Tablet is usually indicated as maintenance therapy after a person completes a platinum-based chemotherapy regimen for ovarian cancer. However, newer studies are evaluating its solitary efficacy in treating different types of cancers.
Can I drive or operate machinery while taking Obrenza 100mg Tablet?
Obrenza 100mg Tablet may cause side effects such as dizziness or fatigue, which could impair your ability to drive or operate machinery safely. If you're unsure, it's best to consult with your healthcare provider for personalized advice based on your specific situation.
