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Характеристики:
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Manufacturer
NEOVII BIOTECH GmbH, GERMANY
Origin of Medicine
Germany
Price for
1 Vial(s) Of 5ml
Salt Composition
Human Rabbit Anti-t Cell Immunoglobulin
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Grafalon 100mg Injection
Description
- Active component: Human rabbit anti-T cell immunoglobulin.
- Use: Treats severe graft-versus-host disease (GvHD).
Graft-versus-host disease (GvHD)
- Occurs when the donor's immune cells (T cells) attack the recipient's body cells.
- Can affect any body part, but most commonly affects the skin, liver, gut, and lungs.
Contraindications
- Severe allergic reaction: Do not receive if you have had a severe allergic reaction to this medication or other monoclonal antibodies.
- Kidney or liver disease: May worsen condition, so it should be avoided.
- Active CNS disease: Can cross the blood-brain barrier and cause problems in the brain.
- Pregnancy or breastfeeding: Can cross the placenta and harm the fetus.
Therapeutic effects
- Depletes T cells, which attack the body's tissues in GvHD.
- Binds to the surface of T cells and activates the immune system to destroy them.
- Can also prevent T cells from developing in the first place.
Interaction with other drugs
- Inform the doctor about all medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products.
- Certain medications may interact with Grafalon 100mg injection, reducing effectiveness or causing undesirable side effects.
Storage
- Store at room temperature from 2–8°C.
- Keep away from moisture, heat, and light.
- Do not freeze.
- Keep away from children and pets.
Administration
- Can be given by intravenous (IV) infusion or intramuscular (IM) injection.
- The IV route is the most common route of administration.
- The doctor chooses the administration route based on the patient's needs and preferences.
Safety advices
- Pregnancy: Unsafe for pregnant women as it can cross the placenta and harm the fetus.
- Breastfeeding: Can pass into breast milk and may harm the baby.
- Lungs: Individuals with respiratory conditions should consult a healthcare provider before taking Grafalon 100mg injection.
- Liver: Individuals with liver conditions should consult with their healthcare provider before taking Grafalon 100mg injection.
- Alcohol: Can increase the risk of side effects from Grafalon 100mg injection, such as low blood counts and infections.
- Driving: Can cause side effects, such as fatigue and dizziness, which can affect your ability to drive.
Side effects
- Serious: Allergic reaction, low blood counts, infection, kidney problems, liver problems, pneumonitis, pulmonary edema, thrombosis, death.
- Common: Fever, chills, nausea, vomiting, diarrhea, headache, muscle pain, fatigue, rash, itching.
Word of advice
- Talk to your doctor about the risks and benefits before taking Grafalon 100mg injection.
- Have your blood counts monitored regularly to identify any problems early on.
- Take precautions against infection as it can weaken your immune system.
- If you experience hives, itching, rash, shortness of breath, swelling of the face, tongue, or throat, and difficulty breathing, seek medical attention immediately.
FAQs
How long does Grafalon 100mg injection treatment last?
- The length of Grafalon 100mg injection treatment depends on the condition being treated. It can range from a few days to several weeks.
What should I do if I experience side effects from Grafalon 100mg injection?
- If you experience any side effects from Grafalon 100mg injection, you should tell your doctor immediately.
What are the long-term risks of Grafalon 100mg injection?
- The long-term risks of Grafalon 100mg injection are not well known. However, some concern is that it may increase the risk of developing autoimmune diseases.
How long does Grafalon 100mg injection take to start working?
- The time it takes for Grafalon 100mg injection to start working varies depending on the individual. In some cases, it may start working within a few days. In other cases, it may take several weeks.
Fact box
- Molecule name: Human rabbit anti-T cell immunoglobulin.
- Therapeutic class: Immunomodulator.
- Pharmacological class: Monoclonal antibody.
- Indications: Graft-versus-host disease (GvHD).
Основные характеристики
Manufacturer
NEOVII BIOTECH GmbH, GERMANY
Origin of Medicine
Germany
Price for
1 Vial(s) Of 5ml
Salt Composition
Human Rabbit Anti-t Cell Immunoglobulin
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