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Uses:

• Advanced and metastatic breast cancer;
• Metastatic gastric cancer.

Mechanism of action:

• The drug contains Trastuzumab as an active constituent.
• It is used in HER2-positive breast cancer, where cancer cells have increased levels of HER2 proteins, which stimulate cancer growth.
• The drug selectively binds to HER2 and stops the growth of cancer cells.

Dosage and administration:

• Administered intravenously;
• Infusion lasts 90 minutes, if well tolerated, subsequent doses are administered within 30 minutes;
• Can be administered before or after surgery.

Contraindications:

• Not recommended for patients under 18 years of age;
• Contraindicated for patients with severe breathing problems or those who need oxygen treatment;
• Consult a doctor if you have heart problems, breathlessness, or have had any other cancer treatment.

Precautions:

• Inform your doctor about all medications, including supplements and herbal medicines, you are taking;
• Keep the drug out of reach of children;
• Store between 2 °C and 8 °C.

Safety advice:

• Pregnancy: consult a doctor before use;
• Breastfeeding: avoid breastfeeding while taking the drug and for at least 7 months after the last dose;
• Lungs: consult a doctor if you have any lung conditions;
• Liver: inform your doctor about liver disorders;
• Alcohol: consult your doctor about alcohol consumption;
• Driving: avoid driving or operating machinery due to possible dizziness and fatigue.

Side effects:

• Serious: heart problems, allergic reactions, kidney problems, breathing difficulties;
• Common: fever, visual disturbances, nosebleeds or runny nose, hair loss, dizziness, nail disorders, weight loss, loss of appetite, bruising, dry mouth, liver inflammation, muscle pain, asthma/lung disorders.

FAQ:

• Q1. Is Canmab 150mg Injection used as a monotherapy in treating breast cancer?
  • A1. No, it is generally given along with chemotherapy medications such as paclitaxel or docetaxel or platinum compounds. Sometimes it is also given with hormonal agents.
• Q2. Does Canmab 150mg Injection cause heart problems?
  • A2. Yes, it can damage the heart muscles. Regular heart check-ups are advised.
• Q3. Can I breastfeed while on treatment with Canmab 150mg Injection?
  • A3. No, it is unsafe to breastfeed. It is advised not to breastfeed for a minimum of 7 months after treatment.
• Q4. Can Canmab 150mg Injection be consumed during pregnancy?
  • A4. No, it is unsafe to consume during pregnancy as it can cause harm to the baby.

Fact box:

• Molecule name: Trastuzumab;
• Therapeutic class: Anti-cancer;
• Pharmacological class: HER2 inhibitor.

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