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₹99 392

Kynteles 300mg Injection

Product Code: MRM_102583
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₹99 392
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Manufacturer
TAKEDA PHARMACEUTICALS INDIA PVT LTD
Origin of Medicine
Japan
Price for
1 Vial(s)
Salt Composition
Vedolizumab
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Kynteles 300mg injection contains the active component of vedolizumab, which belongs to the group of biological medicines known as monoclonal antibodies (MAbs). It is used as a treatment option for adults dealing with moderate to severe cases of ulcerative colitis (inflammation of the large bowel), crohn's disease (inflammation affecting the digestive system), and chronic pouchitis (inflammation of the lining of a pouch created during surgery to treat ulcerative colitis). In these three conditions, your initial course of treatment will typically involve other medications. If you do not respond well to them or experience intolerable side effects, your doctor may prescribe kynteles 300mg injection to help alleviate the signs and symptoms of your condition. 

Do not take this medication if you are under 18 or have allergies to vedolizumab or its components. Additionally, it is essential to inform your doctor if you have an active severe infection, such as tuberculosis (TB), blood poisoning, severe diarrhoea and vomiting (gastroenteritis), or nervous system infection. Another critical point is that you should not take this medication with other biological medicines that suppress your immune system, such as natalizumab or rituximab. 

Inform your healthcare provider if you plan to receive a vaccination or have recently had one. Vedolizumab may impact your response to vaccines. Always provide your doctor with a comprehensive overview of your medical history and the medications you are taking before starting this treatment. If you experience any possible side effects during or after treatment, don't hesitate to notify your doctor promptly.

Uses of Kynteles 300mg InjectionModerate to severe active infections of

  • Ulcerative colitis
  • Crohn's disease
  • Chronic pouchitis

Therapeutic Effects of Kynteles 300mg Injection

The primary mechanism of action of kynteles 300mg injection is to inhibit the activity of a protein on the surfaces of white blood cells, which is responsible for the inflammation associated with ulcerative colitis, crohn's disease, and pouchitis — this inhibition of the protein results in a decrease in the amount of inflammation.

Interaction of Kynteles 300mg Injection with other drugsInform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with kynteles 300mg injection and can cause undesirable side effects, especially if you are under immunosuppressant or corticosteroid therapy.

More Information about Kynteles 300mg Injection
  • Store in refrigerator at (2°C-8°C)
  • Do not freeze
  • Keep this medicine out of the sight and reach of children.
  • Do not dispose of the medication in wastewater or household waste. Always return to the pharmacy when you no longer require the medication.
  • How to consume Kynteles 300mg InjectionThis medicine is given only in a hospital setup by a healthcare provider. It is infused directly into your veins by your physician. Your physician will decide the dosage, frequency, and schedule of the course of treatment based on the severity of your disorder and other factors. Do not miss or skip any scheduled dose. Do not stop the treatment without the doctor's acknowledgment.

    Safety Advices for Kynteles 300mg Injection

      

    Pregnancy

      

    It is unknown whether this medicine is safe during pregnancy. Therefore, it is given when the benefit for the mother outweighs the risk to the foetus. Tell your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant before taking this medication.

      

    Breast Feeding

      

    It is important to let your doctor know if you are breastfeeding or planning to breastfeed because studies suggest that kynteles 300mg injection can pass into breast milk. Your doctor will decide whether to prescribe this medication after carefully weighing the benefits against the risks to your baby.

      

    Lungs

      

    It is unknown whether kynteles 300mg injection is safe for patients suffering from lung disease. Inform your doctor if you have any lung disease before starting the treatment.

      

    Liver

      

    Kynteles 300mg injection can cause significant liver injury that may lead to fatal or the need for liver transplant in some patients. Hence, do not take this injection if you have a severe liver disorder or jaundice. Inform your doctor if you have any liver disease before starting the treatment.

      

    Alcohol

      

    Generally, it is recommended to avoid alcohol consumption during the treatment with kynteles 300mg injection as it can cause significant liver injury. Please consult your doctor for more advice.

      

    Driving

      

    Kynteles 300mg injection can cause mild dizziness during the treatment. If you feel dizzy, do not drive or use heavy machines. Check with your doctor for more advice.

    Side Effects of Kynteles 300mg InjectionSide effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

    Serious

    • Allergic reactions - the signs may include wheezing or difficulty breathing, hives, itching of the skin, swelling, feeling sick, pain at the infusion site, redness of skin
    • Serious infections - the signs may include chills, shivering, high fever, or rash.
    • Progressive Multifocal Leukoencephalopathy - PML (a rare fatal opportunistic infection of the central nervous system)
    • Severe liver injury 

    Common

    • Common cold, fever, and night sweats
    • Pain in joint, back, throat, or limb
    • Headache and tiredness
    • Infections
    • Muscle cramps and weakness
    • Bloated stomach
    • High blood pressure
    • Heartburn
    • Haemorrhoids
    • Eczema and acne (pimples)

    Word of AdviceKynteles 300mg injection is intended exclusively for in-hospital use and administered only by a healthcare provider. If you are a woman of reproductive age, it is advisable to take precautions to avoid pregnancy while receiving this injection; use effective contraception during the treatment period and for at least four and half months after your final treatment. 

    Regarding the safety and effectiveness of kynteles 300mg injection, there aren't any significant differences between elderly and younger patients. However, elderly patients should still undergo close monitoring. If you ever experience symptoms suggestive of progressive multifocal leukoencephalopathy (PML), such as blurred vision, loss of vision, double vision, speech difficulties, weakness in an arm or leg, changes in your gait or balance, persistent numbness, decreased sensation, or memory issues, it is crucial to inform your healthcare provider immediately. 

    This injection may take up to 14 weeks to show its full effect in some patients with very active Crohn's disease. So, inform your doctor if you do not notice any improvement in your condition. Make sure to stick to your scheduled doses throughout your treatment.

    FAQs Q 1. Is kynteles 300mg injection indicated for children?

    No, kynteles 300mg injection should not be administered to children and adolescents under 18.

    Q 2. How long should I take the kynteles 300mg injection?

    If the kynteles 300mg injection works well for you, you can expect to follow a planned treatment regimen for approximately one year. Following this initial period, your doctor will evaluate your progress to determine if the treatment is still providing benefits. If it is, you will continue with the treatment. To ensure that this medicine remains the right choice for you, schedule a review for every 12 months.

    Q 3. What precautions should I take during the treatment with kynteles 300mg injection?

    Kynteles 300mg injection can make you immunocompromised and prone to infections. Hence, to protect yourself, avoid contact with sick people and wash your hands frequently. Inform your doctor immediately if you get a fever, cold, cough, flu-like symptoms, unusual tiredness, or weakness.

    Q 4. What are the most common side effects of kynteles 300mg injection?

    The most common side effects of kynteles 300mg injection are common cold, headache, and joint pain.

    Q 5. Can I receive kynteles 300mg injections while taking other medications?

    Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Tell your healthcare provider if you take or have recently taken any other immunosuppressive medications such as natalizumab, rituximab, corticosteroids, or chemotherapy medications.

    Fact Box of Kynteles 300mg Injection

    Molecule Name: Vedolizumab

    Therapeutic class: Anti-inflammatory agents

    Pharmacological class: Monoclonal antibodies

    Indications: Moderate to severe active infections of  

    1. Ulcerative colitis

    2. Crohn’s disease 

    3. Chronic pouchitis

    Основные характеристики
    Manufacturer
    TAKEDA PHARMACEUTICALS INDIA PVT LTD
    Origin of Medicine
    Japan
    Price for
    1 Vial(s)
    Salt Composition
    Vedolizumab
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