Treats advanced or HER2 Positive metastatic breast cancer.
Therapeutic Effects
Acts against the enzyme called tyrosine kinase.
Prevents the Human epidermal growth factor receptor protein (HER2) and Epidermal growth factor receptors (EGFRs) from signaling, which are produced by breast cancer cells.
Kills cancer cells and slows down their growth.
Interaction with Other Drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment.
Certain medications may interact with Combinib 250mg Tablet and cause undesirable side effects.
Safety Advices
Pregnancy: not safe to consume Combinib 250mg Tablet while pregnant. Consult your doctor and use a reliable contraception method.
Breastfeeding: unsafe during breastfeeding as the medication tends to pass into the breast milk and affect the baby.
Lungs: talk to your doctor if you have any lung conditions before starting treatment.
Liver: use with caution in patients with severe liver disease. Consult your physician for advice.
Alcohol: avoid drinking alcohol while taking Combinib 250mg Tablet as it may cause dizziness.
Driving: may affect your ability to drive or perform activities that require focus. Exercise caution while driving or using machines.
Side Effects
Serious: diarrhea, severe allergic reactions, skin rash, heart problems.
Common: loss of appetite, nausea, vomiting, tiredness, weakness, indigestion, constipation, sore mouth or mouth ulcers, stomach pain, trouble sleeping, back pain, pain in the hands and feet, joint or back pain, cough, breathlessness, headache, nose bleed, hot flush, unusual hair loss, dry skin and itching.
Word of Advice
Take plenty of water during the treatment to prevent dehydration.
Eat a well-balanced diet.
Avoid consuming grapefruit juice while on treatment as it affects how the medicine works.
This medication makes your skin sensitive to the sun and increases the risk of skin rashes. Avoid spending more time in the sunlight, and ensure that you always apply sunscreen with a good SPF before stepping out.
Wash your skin with a soap-free cleanser.
FAQs
What is Combinib 250mg Tablet used for?
Combinib 250mg Tablet is used to treat advanced or HER2 Positive metastatic breast cancer.
What is the most common side effect of Combinib 250mg Tablet?
The most common side effect is diarrhea. To prevent dehydration, consume lots of liquids, such as water or juice. If it is serious, consult your doctor right away.
How does Combinib 250mg Tablet work?
Combinib 250mg Tablet acts against the enzyme called tyrosine kinase. It prevents the Human epidermal growth factor receptor protein (HER2) and epidermal growth factor receptors (EGFRs) from signaling, which breast cancer cells produce. It kills cancer cells and slows down their growth.
Is it safe to take Combinib 250mg Tablet while drinking juice?
No, drinking grapefruit juice while taking Combinib 250mg Tablet can cause harmful interaction. Take this medicine with water only.
Can a pregnant woman take Combinib 250mg Tablet?
No, Combinib 250mg Tablet is unsafe during pregnancy as it may harm the unborn baby. Therefore, it is advisable to tell your healthcare provider if you are pregnant or planning to have a baby before taking this medicine.
Is Combinib 250mg Tablet safe for breastfeeding women?
No, Combinib 250mg Tablet is unsafe during breastfeeding as this medication passes into the breastmilk and affects the baby. It is not to be taken without the doctor's consent.
Fact Box
Molecule name: Lapatinib
Therapeutic class: Antineoplastic agent
Pharmacological class: Kinase inhibitor
Indications: Treats advanced or HER2 Positive metastatic breast cancer.