Indications: Treatment of multiple myeloma and mantle cell lymphoma
Usage
Administered intravenously in the vein or subcutaneously under the skin
Used concomitantly with other chemotherapy medicines like pegylated liposomal doxorubicin, rituximab, cyclophosphamide, doxorubicin, dexamethasone, prednisolone, or thalidomide
For patients who have not started treatment and are ineligible for blood stem cell transplant
Therapeutic Effects
Exerts a toxic effect on cancer cells
Inhibits the 26S proteasome and blocks a major cell signaling pathway
Makes cancer cells sensitive to chemotherapy
Enhances the build-up of a protein and minimizes cancer cell growth and multiplication
Side Effects
Serious: Muscle cramps, confusion, visual disturbances, seizures, headache, breathlessness, swelling of feet, changes in heartbeat, high blood pressure, fainting and tiredness, cough and chest tightness
Common: Pneumonia, loss of appetite, sensitivity, tingling and burning sensation of the skin, nausea, vomiting, diarrhea, mouth ulcers, constipation, muscle and bone pain, hair loss, fever, reduction in blood cell count, reduced kidney function, shivering, infections, itching and redness, dehydration, stomach problems, difficulty sleeping, anxiety, mood swings, depressed mood
Safety Advices
Pregnancy: Unsafe to use during pregnancy unless clearly necessary. Both women of childbearing potential and men must use an effective contraception method during and three months after treatment
Breastfeeding: Unsafe to use during breastfeeding
Lungs: Consult a physician if you have any lung diseases
Liver: Inform your physician before starting this treatment if you have Hepatitis infection or liver disease
Alcohol: Unsafe to consume alcohol with this medication
Driving: Avoid driving or using machinery if you experience side effects like fainting, dizziness, tiredness, or blurred vision
Interactions
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment
Storage
Store unopened vials in the refrigerator (2 °C – 8 °C) and protect them from light
Keep this medicine out of sight and reach of children
FAQ
What is Bortlee 2mg Injection used for?
Bortlee 2mg Injection is mainly indicated to treat mantle cell lymphoma and multiple myeloma.
Can I drive while taking Bortlee 2mg Injection?
Bortlee 2mg Injection may cause dizziness, tiredness, fainting, or blurred vision. Hence, avoid driving and operating heavy machines while this Injection.
How is Bortlee 2mg Injection given?
Bortlee 2mg Injection is administered intravenously in your vein or subcutaneously under the skin by a doctor in a medical facility.
Is it safe to handle Bortlee 2mg Injection while pregnant?
No, Pregnant women should not handle Bortlee 2mg Injection as it contains cytotoxic agents. Using gloves and protective clothing is recommended to prevent skin contact.
What class of chemo is Bortlee 2mg Injection?
Bortlee 2mg Injection is a targeted therapy that belongs to the class of medicines called proteasome inhibitors.
Can I take Bortlee 2mg Injection when I am pregnant?
Avoid taking Bortlee 2mg Injection if you are pregnant, as it can cause harmful effects on the unborn baby. Females should use effective birth control methods during treatment and at least three months after treatment.
I am suffering from a Hepatitis infection. Can I take Bortlee 2mg Injection?
Bortlee 2mg Injection should not be used in patients with hepatitis infection because they might have a repeated attack of hepatitis, which can be fatal. If you have a history of hepatitis B infection, your doctor will carefully check you for signs of active hepatitis B.