Ethyfos 500mg Injection
Active constituent: Amifostine.
Class of medications: Adjunct chemoprotective agents.
Uses:
- Protects the kidneys from the harmful effects of chemotherapy medication (cisplatin) in patients with ovarian cancer.
- Decreases dryness in the mouth caused by radiation treatment after head and neck cancer surgery.
Therapeutic effects:
- The metabolite in Ethyfos 500mg injection is responsible for most cytoprotective and radioprotective effects.
- It is easily absorbed by cells, where it binds to and detoxifies reactive platinum and alkylating agent metabolites, as well as scavenges free radicals.
- Other effects include inhibition of cell death, gene expression alteration, and enzyme activity modification.
Interaction with other drugs:
- Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products.
- Certain medications interact with Ethyfos 500mg injection and reduce its effectiveness by causing undesirable side effects.
Safety advices:
- Do not take Ethyfos 500mg injection if you are allergic to Amifostine or any of the other ingredients.
- Do not take this medicine if you are pregnant or planning for pregnancy.
- Inform your physician if you have any history of liver disease, kidney disease, heart disorders, heart failure, or heart rhythm changes.
- Store the injection at room temperature 20°C to 25°C.
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets.
- If you missed the dosing schedule, inform your healthcare professional immediately and reschedule.
How to consume:
- Ethyfos 500mg injection will be administered to you by a doctor or other healthcare professional in a hospital setting trained in cancer chemotherapy.
- Your doctor will decide the dose, route of administration, and duration of the therapy based on your disease status, severity, and other factors such as body weight, other disease conditions, and age.
- This medicine will be given intravenously (into your vein). Do not self-administer the injection.
Side effects:
- Common: skin rash, nausea, vomiting.
- Serious: decreased blood pressure, severe skin rash, severe hypersensitivity reaction.
FAQs:
Can a patient with kidney problems take Ethyfos 500mg injection? Ethyfos 500mg injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of this injection may not be needed in kidney disease patients. Please consult your doctor for more advice.
Is hypotension a side effect of Ethyfos 500mg injection? Low blood pressure (hypotension) may occur with Ethyfos 500mg injection. Report to your doctor immediately if you have any symptoms of blurred vision, confusion, severe dizziness, faintness, lightheadedness, sweating, or unusual tiredness or weakness.
What if I overdose or take two doses of Ethyfos 500mg injection? If you unknowingly overdosed or took two doses of Ethyfos 500mg injection, immediately inform your healthcare professional and seek medical advice.
What if I miss a dose of Ethyfos 500mg injection? Do not miss your dose. Keep all your appointments with the dosing regularly. In case if you forget or missed an appointment, inform your healthcare professional and reschedule the dosing.
Are there any special dietary instructions I should follow while taking Ethyfos 500mg injection? Unless your doctor tells you to avoid certain foods, continue your normal diet. Consult your doctor for more advice on dietary restrictions.
Fact box:
- Molecule name: Amifostine.
- Therapeutic class: Cytoprotectant.
- Pharmacological class: Adjunct Chemoprotective Agents.
- Indications:
- Protect the kidneys from the harmful effects of chemotherapy medication.
- Treatment of dryness in the mouth after head and neck cancer.